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Volume 17, Number 1—January 2011

Dispatch

Seasonal Influenza A (H1N1) Infection in Early Pregnancy and Second Trimester Fetal Demise

Richard W. LiebermanComments to Author , Natasha Bagdasarian, Dafydd Thomas, and Cosmas Van De Ven
Author affiliations: University of Michigan Health System, Ann Arbor, Michigan, USA

Main Article

Figure 1

Tissue sample from 30-year-old primigravida patient exposed to seasonal influenza (H1N1). A) Intervillous (maternal) spaces with clusters/sheets of histiocytes (chronic intervillositis) and fibrotic fetal chorionic villi with Hofbauer cells–histiocytic inflammation (hematoxylin and eosin stain, original magnification ×200). B) Dual-stained immunofluorescent assay showing antibodies to influenza A virus (H1N1) (tetramethylrhodamine isothiocyanate, red) and cytokeratin (fluorescein isothiocyanate,

Figure 1. Tissue sample from 30-year-old primigravida patient exposed to seasonal influenza (H1N1). A) Intervillous (maternal) spaces with clusters/sheets of histiocytes (chronic intervillositis) and fibrotic fetal chorionic villi with Hofbauer cells–histiocytic inflammation (hematoxylin and eosin stain, original magnification ×200). B) Dual-stained immunofluorescent assay showing antibodies to influenza A virus (H1N1) (tetramethylrhodamine isothiocyanate, red) and cytokeratin (fluorescein isothiocyanate, green) in intravillous (fetal) and intervillous (maternal) space.

Main Article

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