Seasonal Influenza A (H1N1) Infection in Early Pregnancy and Second Trimester Fetal Demise
Figure 2. Tissue sample from 30-year-old primigravida patient exposed to seasonal influenza (H1N1). Electron microscopy (original magnification ×70,000) of maternal intervillous space and fetal chorionic villi, showing intranuclear viral transcription aligning along the nuclear envelope–electron hypodensities (asterisks), and intracytoplasmic viral production in varying stages shown by numerous electron densities (V and ^). Scale bar = 500 nm. Inset: enlarged image of mature virion with capsular projections. Ultrastructural features are characteristic of influenza viruses. Scale bar = 100 nm.