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Volume 17, Number 1—January 2011

CME ACTIVITY - Research

Hepatitis E Virus Infection without Reactivation in Solid-Organ Transplant Recipients, France

Florence Legrand-AbravanelComments to Author , Nassim Kamar, Karine Sandres-Saune, Sebastien Lhomme, Jean-Michel Mansuy, Fabrice Muscari, Federico Sallusto, Lionel Rostaing, and Jacques Izopet
Author affiliations: Author affiliations: Institut National de la Santé et de la Recherche Médicale, Toulouse, France (F. Legrand-Abravanel, N. Kamar, K. Sandres-Saune, S. Lhomme, L. Rostaing, J. Izopet); Centre Hospitalier Universitaire Toulouse, Toulouse (F. Legrand-Abravanel, N. Kamar, K. Sandres-Saune, S. Lhomme, J.-M. Mansuy, F. Muscari, F. Sallusto, L. Rostaing, J. Izopet)

Main Article

Figure 2

Diagnosis and characteristics of 34 patients with hepatitis E virus (HEV) infection, France, January 2004�??December 2008. Ig, immunoglobulin; NA, not available.

Figure 2. Diagnosis and characteristics of 34 patients with hepatitis E virus (HEV) infection, France, January 2004–December 2008. Ig, immunoglobulin; NA, not available.

Main Article

1Based on results from this study, which of the following patients would be anticipated to be at highest risk for acquisition of hepatitis E virus (HEV) infection?

A. A 65-year-old man undergoing kidney transplantation

B. A 45-year-old woman undergoing liver transplantation

C. A 76-year-old man 1 year post liver transplant.

D. A 36-year-old woman 6 months post kidney transplant

2A 49-year-old female patient who is HIV positive undergoes a liver transplant. Six months later she is found to be HEV positive. Which of the following factors would increase her risk to evolve to a chronic infection?

A. Alcohol use

B. Female sex

C. Immunocompromise associated with HIV infection

D. Comorbid hepatitis C virus or hepatitis B virus infection

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