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Volume 17, Number 10—October 2011

Dispatch

Clostridium difficile Infection in Outpatients, Maryland and Connecticut, USA, 2002–2007

Jon Mark HirshonComments to Author , Angela D. Thompson, Brandi Limbago, L. Clifford McDonald, Michelle Bonkosky, Robert Heimer, James Meek, Volker Mai, and Christopher R. Braden
Author affiliations: University of Maryland School of Medicine, Baltimore, Maryland, USA (J.M. Hirshon); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A.D. Thompson, B. Limbago, L.C. McDonald, M. Bonkosky, C. Braden); Yale School of Medicine, New Haven, Connecticut, USA (R. Heimer, J. Meek); University of Florida, Gainesville, Florida, USA (V. Mai)

Main Article

Table 1

Patient risk factors for CDI compared with those of other patients with diarrhea without CDI, Maryland and Connecticut, USA, 2002−2007*

Risk factor No. (%) patients with CDI, n = 43 No. (%) patients with diarrhea but not CDI, n = 1,048 p value†
Illnesses potentially affecting immune status
Lupus 1 (2.3) 4 (0.4) 0.06
Cancer under active treatment 3 (7.0) 40 (3.8) 0.30
HIV/AIDS 2 (4.7) 43 (4.1) 0.86
History of organ transplant 2 (4.7) 22 (2.1) 0.26
Chronic obstructive pulmonary disease (on prednisone)
1 (2.3)
NA
NA
Illnesses potentially affecting gastrointestinal function
Crohn disease 0 (0) 14 (1.3) 0.45
Ulcerative colitis
1 (2.3)
19 (1.8)
0.81
Prior bowel or ulcer surgery 6 (14.0) 69 (6.6) 0.06
Any medical or surgical condition 15 (34.9) 176 (16.8) 0.002
Hospitalized within prior month 14 (32.6) 92 (8.8) <0.001
Antimicrobial drug therapy within prior month 27 (62.8) 231 (22.0) <0.001
No hospitalization or antimicrobial drug therapy within prior month and no predisposing condition 7 (16.3) 698 (66.6) <0.001

*CDI, Clostridium difficile infection; NA, not available.
†Uncorrected χ2.

*CDI, Clostridium difficile infection; NA, not available.
†Uncorrected χ2.

*CDI, Clostridium difficile infection; NA, not available.
†Uncorrected χ2.

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