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Volume 17, Number 10—October 2011
Research

Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus Infection in England and Scotland, 2009–2010

Laurence CalatayudComments to Author , Angie Lackenby, Arlene Reynolds, Jim McMenamin, Nick F. Phin, Maria Zambon, and Richard G. Pebody
Author affiliations: Health Protection Agency, London, UK (L. Calatayud, A. Lackenby, N.F. Phin, M.C. Zambon, R. Pebody); Health Protection Scotland, Glasgow, Scotland, UK (A. Reynolds, J. McMenamin)

Main Article

Table 4

Distribution and reported associations of outcomes (complications, ICU admission, death) for study patients and controls hospitalized for pandemic (H1N1) 2009, England and Scotland, April 27, 2009–April, 30, 2010*

Outcome Case-patients with oseltamivir-resistant strains, n = 34
Controls with oseltamivir-sensitive strains, n = 346
OR (95% CI)
n No. (%) with outcome n No. (%) with outcome Crude Adjusted†
Any complications 25 21 (84.0) 346 76 (22.0) 18.6 (6.0–76.2) 9.0 (2.4–34.3)
Respiratory complications 24 19 (79.2) 346 67 (19.4) 15.8 (5.4–55.6) 6.6 (1.8–23.3)
ICU admission 23 12 (52.01) 205 59 (28.8) 2.3 (1.0–7.1) 2.3 (0.7–7.9)
Death 30 11 (36.7) 322 18 (5.6) 9.8 (3.6–25.4) 2.2 (0.5–9.5)

*n indicates no. patients with information available for that category. ICU, intensive care unit, OR, odds ratio; CI, confidence interval.
†OR adjusted for age, sex, and underlying conditions (e.g., immunosuppression, chronic respiratory diseases).

*n indicates no. patients with information available for that category. ICU, intensive care unit, OR, odds ratio; CI, confidence interval.
†OR adjusted for age, sex, and underlying conditions (e.g., immunosuppression, chronic respiratory diseases).

Main Article

Page created: September 28, 2011
Page updated: September 28, 2011
Page reviewed: September 28, 2011
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