TY - JOUR AU - Sleeman, Katrina AU - Sheu, Tiffany AU - Moore, Zack AU - Kilpatrick, Susan AU - Garg, Shikha AU - Fry, Alicia M. AU - Gubareva, Larisa V. T1 - Influenza B Viruses with Mutation in the Neuraminidase Active Site, North Carolina, USA, 2010–11 T2 - Emerging Infectious Disease journal PY - 2011 VL - 17 IS - 11 SP - 2043 SN - 1080-6059 AB - Oseltamivir is 1 of 2 antiviral medications available for the treatment of influenza B virus infections. We describe and characterize a cluster of influenza B viruses circulating in North Carolina with a mutation in the neuraminidase active site that may reduce susceptibility to oseltamivir and the investigational drug peramivir but not to zanamivir. KW - KW - zanamivir KW - oseltamivir KW - peramivir KW - neuraminidase inhibitor KW - viruses KW - North Carolina KW - influenza KW - influenza B KW - mutation KW - United States DO - 10.3201/eid1711.110787 UR - https://wwwnc.cdc.gov/eid/article/17/11/11-0787_article ER - End of Reference