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Volume 17, Number 12—December 2011

Research

Enterovirus Co-infections and Onychomadesis after Hand, Foot, and Mouth Disease, Spain, 2008

Maria A. BrachoComments to Author , Fernando González-Candelas, Ana Valero, Juan Córdoba, and Antonio Salazar
Author affiliations: Centro Superior de Investigación en Salud Pública, Valencia, Spain (M.A. Bracho); Centro de Investigación Biomédica en Red en Epidemiología y Salud Pública, Barcelona, Spain (M.A. Bracho, F. González-Candelas); Universitat de València, Valencia (F. González-Candelas); University of Edinburgh, Edinburgh, Scotland, UK (A. Valero); Hospital Universitario La Fe, Valencia (J. Córdoba); Centre Salut Pública de València, Valencia (A. Salazar)

Main Article

Table 2

Clinical and epidemiologic data for symptomatic and asymptomatic children and genotyping results of 32 fecal samples collected in the HFMD–onychomadesis outbreak, Valencia, Spain, 2008*

Childcare center Isolate no. Age, y/sex HFMD Date of onset for HFMD Onych Date of onset for onych Date of sampling Serotypes Days from HFMD onset to sampling Days from onych onset to sampling
None 54574 1.5/F Yes Apr 27 Yes May 27 Jun 25 CVA10 58 28
54696 1.7/F Yes May 24 Yes Jun 13 Jul 1 CVA10 37 18
54697 1.7/F Yes May 24 Yes Jun 13 Jul 1 CVA10 37 18
54698 1.7/M Yes Jun 24 Yes Jun 13 Jul 7 CVA10/CVA6 37 18

54682
1.4/F
Yes
Jun 9
Yes
Jun 23
Jun 30
CVA16
21
7
1 54624 2.4/M Yes May 9 Yes Jun15 Jun 26 CVA10 47 41
54628 2.3/F Yes May 3 Yes May 18 Jun 26 CVA10/E9 53 38
54629 1.7/M Yes Apr 18 Yes Jun 28 Jun 26 CVB1 68 28
56643 1.8/M Yes May 1 Yes Jun 19 Jun 26 CVA10 55 37
54582 1.5/M Yes Apr 20 Yes Jun 20 Jun 25 CVA10/CVB1 65 5
54636 1.3/M Yes May 12 Yes Jul 7 Jun 25 CVA10/CVB1 43 –12
54602 2.2/F Yes Apr 15 Yes Jun 9 Jun 25 CVA10/CVA5 70 16
54573 1.4/M No Yes May 2 Jun 25 CVB1 50
54576 2.0/M No Yes May 30 Jun 25 CVA10 25
54622 2.4/M No Yes Jun 3 Jun 26 CVA10 23
54667 1.4/M No No Jun 29 CVA10/CVB1
54572 2.4/M No No Jun 25 CVA10
54575 3.2/F No No Jun 25 CVA10
54579 1.4/M No No Jun 25 CVB1
54601 2.0/M No No Jun 25 CVA10
54599 2.9/M No No Jun 25 CVA10

54632
3.4/M
No

No

Jun 27
CVB1


2 54693 2.8/M Yes May 21 Yes Jun 25 Jul 1 CVB1 40 6
3 54657 2.1/F Yes May 13 Yes Jun 21 Jun 26 CVA6/CVB1 43 5
4 54753 4.2/M No No Jul 2 CVA10
5 54694 1.6/F Yes May 20 Yes Jun 5 Jul 1 CVA6 41 26
6 54633 2.8/M Yes NA Yes May 15 Jun 27 CVA5
7 54678 1.7/F Yes Apr 1 Yes May 14 Jul 1 EV71/CVA5 90 47
8
54720
1.7/F
No

Yes
May 1
Jul 2
EV71

61
9 1023 1.9/F Yes Oct 18 Yes Nov 28 Nov 4 CVA6 16 –31
1215 2.0/F Yes Oct 21 Yes Dec 1 Oct 31 CVA6 9 –24
1031 2.0/M Yes Oct 23 No Nov 4 CVA6 11

*HFMD, hand, foot, and mouth disease; onych, onychomadesis; none, no childcare center attendance; CV, coxsackievirus; E, echovirus; NA, not available; EV, enterovirus.

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