Skip directly to local search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home

Volume 17, Number 2—February 2011

Research

Next-Generation Sequencing of Coccidioides immitis Isolated during Cluster Investigation

David M. Engelthaler, Tom Chiller, James A. Schupp, Joshua Colvin, Stephen M. Beckstrom-Sternberg, Elizabeth M. Driebe, Tracy Moses, Waibhav Tembe, Shripad Sinari, James S. Beckstrom-Sternberg, Alexis Christoforides, John V. Pearson, John Carpten, Paul Keim, Ashley Peterson, Dawn Terashita, and S. Arunmozhi BalajeeComments to Author 
Author affiliations: Author affiliations: Translational Genomics Research Institute, Phoenix, Arizona, USA (D.M. Engelthaler, J.A. Schupp, J. Colvin, S.M. Beckstrom-Sternberg, E.M. Driebe, T. Moses, W. Tembe, S. Sinari, A. Christoforides, J.V. Pearson, J. Carpten, P. Keim); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (T. Chiller, S.A. Balajee); Northern Arizona University, Flagstaff, Arizona, USA (S.M. Beckstrom-Sternberg, J.S. Beckstrom-Sternberg, P. Keim); Los Angeles County Department of Public Health, Los Angeles, California, USA (A. Peterson, D. Terashita)

Main Article

Figure 2

Alignment of Coccidioides immitis whole-genome sequence reads flanking a confirmed single-nucleotide polymorphism (RSv3 supercontig 1, position 6729646, highlighted in blue in panel B) among the 3 cluster isolates. Isolates from patients X, Y, and Z, who had coccidioidomycosis, are shown in panels A, B, and C, respectively. The alignment was created by using SolScape, a short-read sequence-alignment viewer developed in house (J. Pearson et al., unpub. data; tool available upon request). Referenc

Figure 2. Alignment of Coccidioides immitis whole-genome sequence reads flanking a confirmed single-nucleotide polymorphism (RSv3 supercontig 1, position 6729646, highlighted in blue in panel B) among the 3 cluster isolates. Isolates from patients X, Y, and Z, who had coccidioidomycosis, are shown in panels A, B, and C, respectively. The alignment was created by using SolScape, a short-read sequence-alignment viewer developed in house (J. Pearson et al., unpub. data; tool available upon request). Reference sequence position is given at the top of each panel; actual reference sequence is highlighted in white at the center of each panel. Bases differing from the reference sequence are highlighted in pink, green, or yellow.

Main Article

Top of Page

 

Past Issues

Select a Past Issue:

Art in Science - Selections from Emerging Infectious Diseases
Now available for order



CDC 24/7 – Saving Lives, Protecting People, Saving Money. Learn More About How CDC Works For You…

USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO