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Volume 17, Number 2—February 2011

Research

Severe Cases of Pandemic (H1N1) 2009 in Children, Germany

Mathias AltmannComments to Author , Lena Fiebig, Jana Soyka, Rüdiger von Kries, Manuel Dehnert, and Walter Haas
Author affiliations: Author affiliations: Robert Koch Institute, Berlin, Germany (M. Altmann, L. Fiebig, J. Soyka, M. Dehnert, W. Haas); Ludwig-Maximilians-Universität, Munich, Germany (R. von Kries)

Main Article

Table 1

Underlying chronic medical conditions and vaccination status for children with severe pandemic (H1N1) 2009, Germany, 2009–2010*

Characteristic Total Nonsurvivors not in PICU Admitted to PICU
Survivors Nonsurvivors Subtotal p value OR (95% CI)
Underlying chronic medical conditions
Any 67/89 (75) 4/4 (100) 56/76 (74) 7/9 (78) 63/85 (74) 1 1.3 (0.2–13.3)
Neurodevelopmental disorders 51/89 (57) 4/4 (100) 40/75 (53) 7/10 (70) 47/85 (55) 0.501 2.0 (0.4–13.1)
Respiratory disease 31/82 (38) 2/3 (67) 25/70 (36) 4/9 (44) 29/79 (37) 0.718 1.4 (0.3–7.3)
Immunodeficiency 13/80 (16) 1/4 (25) 12/67 (18) 0/9 (0) 12/76 (16) 0.339 0.0 (0.0–2.1)
Cardiac disease
11/84 (13)
0/4 (0)
9/70 (13)
2/10 (20)
11/80 (14)
0.621
1.7 (0.2–10.6)
Vaccination status in patients >6 mo of age
Any influenza 9/56 (16) 0/4 (0) 9/48 (19) 0/4 (0) 9/52 (17) 1 0.0 (0.0–4.7)
Pandemic (H1N1) 2009 5/53 (9) 0/4 (0) 5/45 (11) 0/4 (0) 5/49 (10) 1 0.0 (0.0–9.2)

*Values are no. positive/no with available information (%) except as indicated. PICU, pediatric intensive care unit; OR, odds ratio; CI, confidence interval. ORs were calculated only among patients admitted to the PICU.

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