Novel Picornavirus in Turkey Poults with Hepatitis, California, USA
Kirsi S. Honkavuori, H. L. Shivaprasad, Thomas Briese , Craig Street, David L. Hirschberg, Stephen K. Hutchison, and W. Ian Lipkin
Author affiliations: Author affiliations: Columbia University, New York, New York, USA (K.S. Honkavuori, T. Briese, C. Street, D.L. Hirschberg, W.I. Lipkin); California Animal Health and Food Safety Laboratory System, Tulare, California, USA (H.L. Shivaprasad); 454 Life Sciences, Branford, Connecticut, USA (S.K. Hutchison)
Figure 4. Immunohistologic staining of liver tissues with serum from a turkey poult with turkey viral hepatitis (TVH). Serum sample from PCR-positive poult 394.9 demonstrates turkey hepatitis virus (THV) antigens in clusters of cells in liver tissue of TVH-affected poult 2993A (A) but not in liver sections from nondiseased poult 1927B (B). Sections were counterstained with hematoxylin. Brightfield microscopy images; original magnification ×40.
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