Emerging Infectious Disease ISSN: 1080-6059

Shedding of Pandemic (H1N1) 2009 Virus among Health Care Personnel, Seattle, Washington, USA

Meagan K. Kay

, Danielle M. Zerr, Janet A. Englund, Betsy L. Cadwell, Jane Kuypers, Paul Swenson, Tao Sheng Kwan-Gett, Shaquita L. Bell, and Jeffrey S. Duchin

Author affiliations: Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M. Kay, B.L. Cadwell); Public Health–Seattle and King County, Seattle, Washington, USA (M. Kay, P. Swenson, T.S. Kwan-Gett, J.S. Duchin); Seattle Children’s Hospital, Seattle (D.M. Zerr, J.A. Englund, S.L. Bell); University of Washington, Seattle (J. Kuypers, T.S. Kwan-Gett, J.S. Duchin)

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Figure 2

Virus RNA concentrations over time among health care personnel infected with pandemic (H1N1) 2009 virus, Seattle, Washington, USA. Each colored line represents a virus RNA concentration for an infected person tested from symptom onset until the first of 2 consecutive negative results by real-time reverse transcription–PCR (RT-PCR) for pandemic (H1N1) 2009 virus. Persons who had virus detected by real-time RT-PCR only once are indicated by solid circles. The lower detection limit of the real-time

Figure 2. Virus RNA concentrations over time among health care personnel infected with pandemic (H1N1) 2009 virus, Seattle, Washington, USA. Each colored line represents a virus RNA concentration for an infected person tested from symptom onset until the first of 2 consecutive negative results by real-time reverse transcription–PCR (RT-PCR) for pandemic (H1N1) 2009 virus. Persons who had virus detected by real-time RT-PCR only once are indicated by solid circles. The lower detection limit of the real-time RT-PCR was 3 log₁₀ copies/mL. Numbers of persons with virus RNA concentrations below the detection limit for each day after symptom onset are shown in parentheses below the x-axis. Sixteen infected persons were receiving oseltamivir.

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