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Volume 17, Number 4—April 2011

Dispatch

Bacterial Meningitis and Haemophilus influenzae Type b Conjugate Vaccine, Malawi

David W. McCormickComments to Author  and Elizabeth M. Molyneux
Author affiliations: Author affiliations: University of Michigan, Ann Arbor, Michigan, USA (D.W. McCormick); College of Medicine, Blantyre, Malawi (E.M. Molyneux)

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Table

Causes of bacterial meningitis among patients at Queen Elizabeth Central Hospital, Blantyre, Malawi 1997–2009

Culture organism No. cases (annual mean ± SE)
p value
1997–2002* 2003–2009
Streptococcus pneumoniae 373 (74.6 ± 4.83) 547 (78.1 ± 5.69) 0.66
Haemophilus influenzae type b 266 (53.2 ± 5.51) 68 (9.7 ± 1.91) <0.0001
Neisseria meningitides 78 (15.6 ± 4.27) 26 (3.7 ± 1.12) 0.0106
Salmonella spp.† 62 (12.4 ± 4.27) 65 (9.3 ± 1.91) 0.48
Other‡ 40 (8.0 ± 2.70) 66 (9.4 ± 2.51) 0.71
No growth 100 (25.8 ± 3.40) 205 (25.1 ± 1.65) 0.85

*Excludes data from 2001.
Salmonella enterica serovar Typhimurium (79), S. enterica serovar Enteriditis (22), S. enterica serovar Typhi (14), and other Salmonella spp. (9). These numbers reflect actual case counts. Numbers were adjusted for missing data.
‡Includes Klebsiella spp. (4), Staphylococcus aureus (5), Staphylococcus epidermidis (2), Escherichia coli (5), Brevundimonas vesicularis (1), Pseudomonas aeruginosa (2), Streptococcus pyogenes (6), H. influenzae type C (4), H. influenzae nontype b (6), group B streptococci (2), group A streptococci (1), and other species and unidentified species observed by using Gram staining.

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