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Volume 17, Number 4—April 2011

CME ACTIVITY - Research

Mumps Complications and Effects of Mumps Vaccination, England and Wales, 2002–2006

Chee-Fu YungComments to Author , Nick Andrews, Antoaneta Bukasa, Kevin E. Brown, and Mary E. Ramsay
Author affiliations: Authors affiliation: Health Protection Agency Centre for Infections, London, UK

Main Article

Table 2

Association between receipt of vaccination and mumps complications, adjusted for age and sex, England and Wales, April 1, 2002–March 31, 2006*

Complication
Vaccine dose
No. cases/total cases (%)
Unadjusted OR (95% CI)
Adjusted OR (95% CI)
Hospitalization 0 317/8,298 (3.8) 1 1
1 122/6,312 (1.9) 0.50 (0.40–0.61) 0.54 (0.43–0.68)

2
13/914 (1.4)
0.36 (0.21–0.64)
0.45 (0.25–0.80)
Orchitis† 0 356/4,574 (7.8) 1 1
1 123/3,241 (3.8) 0.44 (0.36– 0.55) 0.72 (0.56–0.93)

2
7/475 (1.5)
0.17 (0.08–0.37)
0.64 (0.28–1.44)
Meningitis 0 42/8,298 (0.5) 1 1
1 10/6,312 (0.2) 0.31 (0.16–0.62) 0.28 (0.14–0.56)

2
1/914 (0.1)
0.22 (0.03–1.57)
0.17 (0.02–1.26)
Pancreatitis 0 26/8,298 (0.3) 1 1
1 12/6,312 (0.2) 0.61 (0.31–1.20) 0.95 (0.41–2.19)
2 0/914 0 (0–1.34)‡

*OR, odds ratio; CI, confidence interval; –, not estimable.
†Adjusted for age only.
‡Exact CI.

Main Article

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