Volume 17, Number 5—May 2011
Research
Genotypic Profile of Streptococcus suis Serotype 2 and Clinical Features of Infection in Humans, Thailand
Anusak Kerdsin, Surang Dejsirilert, Parichart Puangpatra, Saowalak Sripakdee, Koranan Chumla, Nitsara Boonkerd, Pitimol Polwichai, Susumu Tanimura, Dan Takeuchi, Tatsuya Nakayama, Shota Nakamura, Yukihiro Akeda, Marcelo Gottschalk, Pathom Sawanpanyalert, and Kazunori Oishi
Table 4
Genotypic features of Streptococcus suis serotype 2 as risk factor for meningitis*
| Feature | Clinical category, no. (%) strains |
p value | ||
|---|---|---|---|---|
| All, n = 158 | Meningitis, n = 93 | Nonmeningitis, n = 65 | ||
| Sequence type | ||||
| 1 | 98 (62.0) | 73 (78.5) | 25 (38.5) | <0.0001† |
| 104 | 40 (25.3) | 6 (6.5) | 34 (52.3) | <0.0001‡ |
| 25 | 11 (7.0) | 7 (7.5) | 4 (6.2) | 0.478 |
| 28 | 3 (1.9) | 2 (2.2) | 1 (1.5) | 0.632 |
| 103 | 3 (1.9) | 2 (2.2) | 1 (1.5) | 0.655 |
| 126 |
3 (1.9) |
2 (2.2) |
0 |
0.201 |
| VAG profile | ||||
| epf+/sly+/mrp+ | 97 (61.4) | 72 (79.6) | 25 (35.4) | <0.0001† |
| epf+/sly+/mrps | 3 (25.3) | 3 (3.2) | 0 (0) | 0.201 |
| epf–/sly+/mrp– | 40 (25.3) | 6 (6.5) | 34 (52.3) | <0.0001‡ |
| epf– /sly–/mrp* | 10 (6.3) | 6 (6.5) | 4(6.2) | 0.607 |
| epf–/sly–/mrp+ | 7 (4.4) | 5 (5.3) | 2 (3.1) | 0.392 |
| epf–/sly+/mrp+ |
1 (1.0) |
1 (1.1) |
0 (0) |
1 |
| 89K PAI profile, 89K PAI+ | 98 (62.0) | 70 (75.3) | 28 (43.1) | <0.0001† |
*Statistical analyses were performed by using the χ2 or Fisher exact test. VAG, virulence-associated gene; 89K PAI, ≈89-kb pathogenicity island.
†Significant association with the meningitis category.
‡Significant association with the nonmeningitis category.
