TY - JOUR AU - Oishi, Kazunori AU - Dejsirilert, Surang AU - Puangpatra, Parichart AU - Sripakdee, Saowalak AU - Chumla, Koranan AU - Boonkerd, Nitsara AU - Polwichai, Pitimol AU - Tanimura, Susumu AU - Takeuchi, Dan AU - Nakayama, Tatsuya AU - Nakamura, Shota AU - Akeda, Yukihiro AU - Gottschalk, Marcelo AU - Sawanpanyalert, Pathom AU - Kerdsin, Anusak T1 - Genotypic Profile of Streptococcus suis Serotype 2 and Clinical Features of Infection in Humans, Thailand T2 - Emerging Infectious Disease journal PY - 2011 VL - 17 IS - 5 SP - 835 SN - 1080-6059 AB - To examine associations between clinical features of Streptococcus suis serotype 2 infections in humans in Thailand and genotypic profiles of isolates, we conducted a retrospective study during 2006–2008. Of 165 patients for whom bacterial cultures of blood, cerebrospinal fluid, or both were positive for S. suis serotype 2, the major multilocus sequence types (STs) found were ST1 (62.4%) and ST104 (25.5%); the latter is unique to Thailand. Clinical features were examined for 158 patients. Infections were sporadic; case-fatality rate for adults was 9.5%, primarily in northern Thailand. Disease incidence peaked during the rainy season. Disease was classified as meningitis (58.9%) or nonmeningitis (41.1%, and included sepsis [35.4%] and others [5.7%]). Although ST1 strains were significantly associated with the meningitis category (p<0.0001), ST104 strains were significantly associated with the nonmeningitis category (p<0.0001). The ST1 and ST104 strains are capable of causing sepsis, but only the ST1 strains commonly cause meningitis. KW - Streptococcus suis KW - serotype 2 KW - meningitis KW - sepsis KW - sequence typing KW - bacteria KW - research KW - Thailand DO - 10.3201/eid1705.100754 UR - https://wwwnc.cdc.gov/eid/article/17/5/10-0754_article ER - End of Reference