*IV, intravenous; VFR, travelers born in malaria-endemic countries visiting friends and relatives; NA, not available; TR, returning travelers of European origin; po, per os; DIC, disseminated intravascular coagulation.
†Patient received IV artesunate after treatment was begun with IV quinine/doxycycline. The treatment regimen was changed because of quinine-associated hypotension and bradycardia during the first dose of quinine.
‡Artesunate, 1.2 mg/kg, all doses.
§Artesunate, 2.4 mg/kg, first dose; 1.2 mg/kg, subsequent doses.
¶Patient received chloroquine/primaquine for 4 days before admission.
#Artesunate, 2.4 mg/kg, all doses.
**Patient received 1 dose of artemether/lumefantrine before transfer to avoid a delay in treatment initiation.
††Clindamycin, 20 mg/kg/d, divided into 4 doses (20).
‡‡Patient received 1 dose of IV quinine before transfer to the Berlin treatment center to avoid a delay in treatment initiation.
§§Parasitemia level <1%.
¶¶One dose artemether/lumefantrine was given on day 2 before IV artesunate treatment was given because of deteriorating clinical status of the patient.