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Volume 17, Number 6—June 2011

Dispatch

Immunologic Changes during Pandemic (H1N1) 2009, China

Hong-Hui Shen1, Jun Hou1, Wei-Wei Chen, Bing-Ke Bai, Hai-Bin Wang, Tong-Sheng Guo, Ai-Xia Liu, Yong-Li Li, Min Zhao, Pan-Yong Mao, Jin Li, Bo-An LiComments to Author , and Yuan-Li Mao1
Author affiliations: Author affiliation: Beijing 302 Hospital, Beijing, People’s Republic of China

Main Article

Table

Flow cytometric analysis of peripheral blood lymphocyte subsets for 28 patients with pandemic (H1N1) 2009 at hospitalization, China*

Lymphocyte subset No. positive/no. tested (%)
CD45 <1,500 cells/mm3
21/28 (75.0)
CD3
<690 cells/mm3 9/28 (32.1)
<55%
4/28 (14.3)
CD4
<400 cells/mm3 13/28 (46.4)
<31%
8/28 (28.6)
CD8
<190 cells/mm3 3/28 (10.7)
<13%
0/28 (0)
B cells
<90 cells/mm3 1/28 (3.6)
<6%
0/28 (0)
Natural killer cells
>590 cells/mm3 1/28 (3.6)
>27%
4/28 (14.3)
Ratio of CD4:CD8 cells <1.4 14/28 (50.0)

*Lymphocyte subsets were defined as the following combinations: CD3+/CD45+ for CD3 T-lymphocytes; CD3+/CD4/+/CD45+ for CD4 T-lymphocytes; CD3+/CD8+/CD45+ for CD8 T-lymphocytes; CD19+/CD45+ for B-lymphocytes; and CD3+/CD(16+56)+/CD45+ for natural killer cells.
†CD45 lymphocyte count was designated the total lymphocyte count.

Main Article

1These authors contributed equally to this article.

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