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Volume 17, Number 6—June 2011
Letter

Macrolide Resistance–associated 23S rRNA Mutation in Mycoplasma genitalium, Japan

Yasushi Shimada, Takashi DeguchiComments to Author , Keita Nakane, Mitsuru Yasuda, Shigeaki Yokoi, Shin-ichi Ito, Masahiro Nakano, Shin Ito, and Hiroaki Ishiko
Author affiliations: Author affiliations: Gifu University, Gifu, Japan (Y. Shimada, T. Deguchi, K. Nakane, M. Yasuda, S. Yokoi, S.-I. Ito, M. Nakano); Mitsubishi Chemical Medience Corporation, Chiba, Japan (Y. Shimada, H. Ishiko); iClinic, Sendai, Japan (S. Ito)

Main Article

Table

Mutations in the 23S rRNA gene and amino acid changes in L4 and L22 ribosomal proteins of 25 Mycoplasma genitalium strains in the pretreatment urine specimens of men with nongonococcal urethritis, Japan

No. urine specimens
Mutation in the 23S rRNA gene*
Amino acid change
L4
L22
1 A2059G Gly93Glu/Asp109Glu
1 T2185G Val84Gly
1 T2185G GLu128Gly
2 T2185G
1 Pro81Ser
1 Tyr135Pro
1 Ser81Thr
1 Met82Lys
1 Asn112Asp
1 Arg114Lys
14

*Nucleotide position in the 23S rRNA gene is according to Escherichia coli numbering. –, identical to the type strain.

Main Article

Page created: August 03, 2011
Page updated: August 03, 2011
Page reviewed: August 03, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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