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Volume 17, Number 7—July 2011

Research

Severe Plasmodium knowlesi Malaria in a Tertiary Care Hospital, Sabah, Malaysia

Timothy William, Jayaram Menon, Giri Rajahram, Leslie Chan, Gordon Ma, Samantha Donaldson, Serena Khoo, Charlie Fredrick, Jenarun Jelip, Nicholas M. Anstey, and Tsin Wen YeoComments to Author 
Author affiliations: Author affiliations: Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysian Borneo (T. William, J. Menon, G. Rajahram, L. Chan, G. Ma, S. Donaldson, S. Khoo, C. Fredrick); Department of Health, Kota Kinabalu, Malaysia (J. Jelip); Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia (N.M. Anstey, T.W. Yeo); Royal Darwin Hospital, Darwin (N.M. Anstey, T.W. Yeo)

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Table 1

Baseline demographic characteristics and clinical features of patients with severe and uncomplicated Plasmodium knowlesi malaria, Sabah, Malaysia, 2007–2009

Characteristic Uncomplicated disease, n = 34 Severe disease, n = 22
Mean age, y* (range) 37 (20–66) 57 (22–84)
No. (%) female patients† 3 (8.8) 8 (36.3)
Self-reported previous malaria, no. patients 1 0
History of chronic illness, % 18 10
Mean duration of illness, d (range)
5.0 (1–30)
5.2 (2–7)
Symptoms
Fever, % 100 96
Headache, % 62 57
Diarrhea, %
21
24
Physical findings
Mean temperature (range) 38.2°C (36.5–41°C) 37.6°C (36.7–39.2 °C)
Mean respiratory rate, breaths/min* (range) 20 (14–26) 26 (15–50)
Mean pulse rate, beats/min (range) 95 (69–151) 100 (76–130)
Mean arterial pressure, mm Hg (range)* 85 (61–106) 74 (42–106)
Mean oxygen saturation, % (range)* 98 (92–100), n = 20 88 (56–100), n = 17

*p<0.05 by Mann Whitney U test.
†p<0.05 by χ2 test.

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