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Volume 17, Number 7—July 2011

Research

Severe Plasmodium knowlesi Malaria in a Tertiary Care Hospital, Sabah, Malaysia

Timothy William, Jayaram Menon, Giri Rajahram, Leslie Chan, Gordon Ma, Samantha Donaldson, Serena Khoo, Charlie Fredrick, Jenarun Jelip, Nicholas M. Anstey, and Tsin Wen YeoComments to Author 
Author affiliations: Author affiliations: Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysian Borneo (T. William, J. Menon, G. Rajahram, L. Chan, G. Ma, S. Donaldson, S. Khoo, C. Fredrick); Department of Health, Kota Kinabalu, Malaysia (J. Jelip); Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia (N.M. Anstey, T.W. Yeo); Royal Darwin Hospital, Darwin (N.M. Anstey, T.W. Yeo)

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Table 2

Laboratory results for patients with severe and uncomplicated Plasmodium knowlesi malaria, Sabah, Malaysia, 2007–2009*

Laboratory result Uncomplicated disease, n = 34 Severe disease, n = 22
Parasite count† 3 (1–4) 4 (2–4)
Hemoglobin concentration, gm/dL† 13.4 (9.1–17.6) 11.3 (6.2–16.8)
Leukocyte count, × 103 cells/µL† 6.3 (3.4–15.3) 12.7 (3.5–21.6)
Neutrophil count, × 103 cells/µL† 3.9 (1.4–10.1) 9.0 (2.73–16.9)
Lymphocyte count × 103 cells/µL† 1.6 (0.6–3.3) 2.3 (0.24–6.4)
Prothrombin time, s† 13.8 (10.6–17.5)‡ 14.9 (11.7–21)§
Partial thromboplastin time, s† 40 (29.9–57.6)‡ 57 (31–136)§
Platelet count × 103 cells/µL† 72 (21–227) 40 (12–130)
Serum creatinine, µmol/L† 92.6 (57–168) 289 (53–819)
Serum sodium concentration, mmol/L† 136 (128–146) 131 (123–140)
Serum total bilirubin, µmol/L 25.2 (4–48)¶ 173 (11–660)
Serum albumin, gm/dL† 38 (26–73)# 22 (18–27)

*All values are mean (range).
†p<0.05 by Student t test or Mann Whitney U test.
‡n = 23.
§n = 19.
¶n = 15.
#n = 13.

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