Volume 17, Number 7—July 2011
CME ACTIVITY
Hantavirus Pulmonary Syndrome, United States, 1993–2009
Adam MacNeil
, Thomas G. Ksiazek, and Pierre E. Rollin
, Thomas G. Ksiazek, and Pierre E. RollinTable 3
Clinical characteristics of HPS case-patients, United States, 1993–2009*
| Characteristic | No. patients reporting characteristic/no. patients for whom data were available for that characteristic (%) |
p value† | ||
|---|---|---|---|---|
| All | Died | Survived | ||
| Fever | 356/397 (90) | 116/132 (88) | 239/264 (91) | 0.414 |
| Thrombocytopenia‡ | 405/418 (97) | 131/134 (98) | 273/283 (96) | 0.477 |
| Increased hematocrit‡ | 261/389 (67) | 103/130 (79) | 157/258 (61) | <0.001 |
| Increased creatinine level‡ | 120/286 (42) | 54/93 (58) | 66/193 (34) | <0.001 |
| Increased leukocyte count‡ | 169/234 (72) | 72/83 (87) | 96/150 (64) | <0.001 |
| Chest radiograph showing unexplained bilateral infiltrates or suggestive of ARDS | 390/406 (96) | 135/141 (96) | 255/265 (96) | 0.812 |
| Need for supplemental oxygen | 390/405 (96) | 134/135 (99) | 255/269 (95) | 0.025 |
| Intubation of patient | 265/430 (62) | 129/139 (93) | 135/290 (47) | <0.001 |
*HPS, hantavirus pulmonary syndrome; ARDS, acute respiratory distress syndrome.
†By χ2 test for difference in the proportion of HPS case-patients with a clinical characteristic who died and those who survived.
‡Based on qualitative data (yes or no) regarding clinical characteristic from case investigation form. For a small number of case-patients for whom qualitative data were incomplete, but for whom laboratory values were available, qualitative values were assigned on the basis of described clinical cutoff values (24).
