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Volume 17, Number 7—July 2011

CME ACTIVITY - Synopsis

Neurognathostomiasis, a Neglected Parasitosis of the Central Nervous System

Juri Katchanov, Kittisak Sawanyawisuth, Verajit Chotmongkol, and Yukifumi NawaComments to Author 
Author affiliations: Author affiliations: Mahidol University, Bangkok, Thailand (J. Katchanov, Y. Nawa); Khon Kaen University, Khon Kaen, Thailand (K. Sawanyawisuth, V. Chotmongkol)

Main Article

Table 1

Clinical presentation of 248 patients with neurognathostomiasis*

Syndrome Probable entry portal entry Clinical signs and symptoms No. (%) cases
Radiculomyelitis/myelitis/ myeloencephalitis Intervertebral foramina along the spinal nerves and vessels Sharp radicular pain and a spinal syndrome (paraplegia, monoplegia, quadriplegia, bladder dysfunction, sensory disturbances), can progress to cerebral involvement (myeloencephalitis) 140 (55)
Meningitis/ meningoencephalitis Neural foramina of the skull base along the cranial nerves and vessels Severe headache, stiffness of the neck, cranial nerve palsies, disturbance of consciousness, focal neurologic signs 77 (30)
Intracerebral hemorrhage Intervertebral or neural foramina Headache, sudden-onset focal neurologic signs 21 (8)
Subarachnoid hemorrhage
Intervertebral or neural foramina
Thunderclap headache, meningeal signs
16 (7)
*Because the larvae migrate, patients can have sequential signs and symptoms; thus, the total number of clinical syndromes shown exceeds the number of reported patients.

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