Aichi Virus Shedding in High Concentrations in Patients with Acute Diarrhea
Jan Felix Drexler, Sigrid Baumgarte, Luciano Kleber de Souza Luna, Monika Eschbach-Bludau, Alexander N. Lukashev, and Christian Drosten
Author affiliations: Author affiliations: University of Bonn Medical Centre, Bonn, Germany (J.F. Drexler, M. Eschbach-Bludau, C. Drosten); Institute of Hygiene and the Environment, Hamburg, Germany (S. Baumgarte); Bernhard Nocht Institute for Tropical Medicine, Hamburg (L.K. de Souza Luna); Chumakov Institute of Poliomyelitis and Viral Encephalitides, Moscow, Russia (A.N. Lukashev)
Figure 2. Neighbor-joining phylogeny of Aichi virus (AiV) viral protein 1 gene of strains from study of AiV in patients with acute diarrhea (boldface), Germany, compared with strains from GenBank. The tree was generated by using MEGA4 (www.megasoftware.net) using the maximum-composite likelihood nucleotide substitution model and complete deletion option. Porcine kobuvirus was used as an outgroup (branch truncated as indicated by slashed lines). Bootstrap values from 1,000 reiterations are depicted next to root points. The final dataset corresponded to nucleotide positions 3,034–3,663 in AiV GenBank accession no. AB040749. Scale bar indicates number of base substitutions per site.
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