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Volume 17, Number 8—August 2011

CME ACTIVITY - Research

Deaths Associated with Human Adenovirus-14p1 Infections, Europe, 2009–2010

Michael J. CarrComments to Author , Adriana E. Kajon, Xiaoyan Lu, Linda Dunford, Paul O’Reilly, Paul Holder, Cillian F. De Gascun, Suzie Coughlan, Jeff Connell, Dean D. Erdman, and William W. Hall
Author affiliations: Author affiliations: National Virus Reference Laboratory–University College Dublin, Dublin, Ireland (M.J. Carr, L. Dunford, P. O’Reilly, P. Holder, C.F. De Gascun, S. Coughlan, J. Connell, W.W. Hall); Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA (A.E. Kajon); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (X. Lu, D.D. Erdman)

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Table

Clinical characteristics of patients with confirmed HAdV-14p1, Ireland, July 1, 2009–July 31, 2010*

Case no. Age/sex Location Sample date Sample type Previous condition Clinical characteristics Outcome
1 4 y/M Dublin 2009 Nov NPA Pierre Robin syndrome (craniofacial abnormality) Fever, tachypnea, cough Survived
2 7 mo/M Dublin 2010 Mar NPA None known Bronchiolitis Survived
3 1 mo/M Dublin 2010 May NPA None known Bronchiolitis, diarrhea, vomiting Survived
4 8 d/F Dublin 2010 May Serum (×2), urine Preterm birth at 35 weeks’ gestation Hypotonic, abnormal LFT results Died
5 46 y/F Kilkenny 2010 May Other/lung biopsy Smoking, high BMI Community-acquired pneumonia, sepsis Died
6 34 y/M Dublin 2010 May BAL Post-BMT, neutropenic Unilateral pulmonary infiltrate, fever Died
7 4 mo/M Dublin 2010 Jul NPA None known Bronchiolitis, diarrhea, vomiting Survived
8 14 d/M Cork 2010 Jul Plasma (×2) None known ARDS Survived
9 48 y/M Dublin 2010 Jul BAL HIV+ (RNA <50) HCV+ (RNA not detected); CD4 436 (15%) Pneumonia Survived

*HAdV-14p1, human adenovirus serotype 14p1; NPA, nasopharyngeal aspirate; LFT, liver function test; BMI, body mass index; BAL, bronchoalveolar lavage; BMT, bone marrow transplant; ARDS, acute respiratory distress syndrome; +, positive; HCV, hepatitis C virus; CD4, CD4 cells/mL.

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