Volume 17, Number 8—August 2011
CME ACTIVITY
Deaths Associated with Human Adenovirus-14p1 Infections, Europe, 2009–2010
Michael J. Carr
, Adriana E. Kajon, Xiaoyan Lu, Linda Dunford, Paul O’Reilly, Paul Holder, Cillian F. De Gascun, Suzie Coughlan, Jeff Connell, Dean D. Erdman, and William W. Hall
, Adriana E. Kajon, Xiaoyan Lu, Linda Dunford, Paul O’Reilly, Paul Holder, Cillian F. De Gascun, Suzie Coughlan, Jeff Connell, Dean D. Erdman, and William W. HallTable
Clinical characteristics of patients with confirmed HAdV-14p1, Ireland, July 1, 2009–July 31, 2010*
| Case no. | Age/sex | Location | Sample date | Sample type | Previous condition | Clinical characteristics | Outcome |
|---|---|---|---|---|---|---|---|
| 1 | 4 y/M | Dublin | 2009 Nov | NPA | Pierre Robin syndrome (craniofacial abnormality) | Fever, tachypnea, cough | Survived |
| 2 | 7 mo/M | Dublin | 2010 Mar | NPA | None known | Bronchiolitis | Survived |
| 3 | 1 mo/M | Dublin | 2010 May | NPA | None known | Bronchiolitis, diarrhea, vomiting | Survived |
| 4 | 8 d/F | Dublin | 2010 May | Serum (×2), urine | Preterm birth at 35 weeks’ gestation | Hypotonic, abnormal LFT results | Died |
| 5 | 46 y/F | Kilkenny | 2010 May | Other/lung biopsy | Smoking, high BMI | Community-acquired pneumonia, sepsis | Died |
| 6 | 34 y/M | Dublin | 2010 May | BAL | Post-BMT, neutropenic | Unilateral pulmonary infiltrate, fever | Died |
| 7 | 4 mo/M | Dublin | 2010 Jul | NPA | None known | Bronchiolitis, diarrhea, vomiting | Survived |
| 8 | 14 d/M | Cork | 2010 Jul | Plasma (×2) | None known | ARDS | Survived |
| 9 | 48 y/M | Dublin | 2010 Jul | BAL | HIV+ (RNA <50) HCV+ (RNA not detected); CD4 436 (15%) | Pneumonia | Survived |
*HAdV-14p1, human adenovirus serotype 14p1; NPA, nasopharyngeal aspirate; LFT, liver function test; BMI, body mass index; BAL, bronchoalveolar lavage; BMT, bone marrow transplant; ARDS, acute respiratory distress syndrome; +, positive; HCV, hepatitis C virus; CD4, CD4 cells/mL.
