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Volume 17, Number 8—August 2011

Dispatch

Human Parvovirus 4 as Potential Cause of Encephalitis in Children, India

Laura A. Benjamin, Penny Lewthwaite, Ravi Vasanthapuram, Guoyan Zhao, Colin Sharp, Peter Simmonds, David Wang, and Tom SolomonComments to Author 
Author affiliations: Author affiliations: University of Liverpool Institute of Infection and Global Health, Liverpool, UK (L.A. Benjamin, P. Lewthwaite, T. Solomon); Walton Centre National Health Service Foundation Trust, Liverpool (L.A. Benjamin, T. Solomon); Vijayanagar Institute of Medical Sciences, Bellary, India (R. Vasanthapuram); Washington University, St. Louis, Missouri, USA (G. Zhao, D. Wang); University of Edinburgh, Edinburgh, Scotland (C. Sharp, P. Simmonds)

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Table 2

Percent divergence of the nonstructural coding region of human PARV4–positive encephalitis patients VES065 and VES085, compared with previously described PARV4 variants*

Patient or genotype Genotype 3,
aa (nt), n = 1 Genotype 2,
aa (nt), n = 7 Genotype 1,
aa (nt), n = 11 VES085 serum, aa (nt), n = 1 VES085 CSF, aa (nt), n = 1 VES065 CSF, aa (nt), n = 1
VES065 CSF, n = 1 9.5 (3.5) 3.7 (1.5) 10.3 (3.7) 0.2 (0.0) 0.2 (0.0)
VES085 CSF, n = 1 9.4 (3.5) 3.6 (1.5) 10.2 (3.7) 0.0 (0.0)
VES085 serum, n = 1 9.4 (3.5) 3.6 (1.5) 10.2 (3.7)
Genotype 1, n = 11 8.0 (2.6) 9.3 (2.9) 0.9 (0.6)
Genotype 2, n = 7 8.6 (2.7) 1.8 (0.7)
Genotype 3, n = 1

*PARV4, human parvovirus 4; CSF, cerebrospinal fluid.

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