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Volume 17, Number 9—September 2011

Research

Seroepidemiologic Study of Pandemic (H1N1) 2009 during Outbreak in Boarding School, England

Sandra Johnson, Chikwe IhekweazuComments to Author , Pia Hardelid, Nika Raphaely, Katja Hoschler, Alison Bermingham, Muhammad Abid, Richard Pebody, Graham Bickler, John Watson, and Éamonn O’Moore
Author affiliations: Author affiliations: Health Protection Agency, London, UK (S. Johnson, C. Ihekweazu, P. Hardelid, K. Hoschler, A. Bermingham, R. Pebody, G. Bickler, J. Watson); Health Protection Agency, Oxfordshire, UK (N. Raphaely, M. Abid, É. O’Moore)

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Table 2

Association of demographic characteristics and interventions with study participants’ reports of ARI during outbreak of pandemic (H1N1) 2009 at a boarding school, England*

Variable
No. participants
No. (%) with ARI
Odds ratio (95% CI)
Total 695 237 (34.1)
Demographics
Category
Students 469 187 (39.9) 2.53 (1.75–3.65)
Staff 226 50 (22.1) 1
Age group, y
13–15 219 75 (34.2) 1
16–18 250 112 (44.8) 1.55 (1.06–2.28)
20–49 111 32 (28.8) 0.70 (0.42–1.15)
>50 87 18 (20.7) 0.48 (0.26–0.86)
Sex, staff only†
F 109 24 (22.0) 1
M 117 26 (22.2) 0.98 (0.52–1.83)
Role, staff only
Nonteaching 135 26 (19.3) 1
Teaching
85
23 (27.1)
1.48 (0.78–2.82)
Interventions
Took antiviral drugs
No 198 81 (40.9) 1
Yes 393 110 (28.0) 0.55 (0.38–0.79)
Use of antiviral drugs: PEP vs. treatment dose
No antiviral drugs 198 81 (40.9) 1
Yes, PEP 352 78 (22.2) 0.40 (0.27–0.59)
Yes, treatment dose 41 32 (78.1) 4.87 (2.20–10.77)
Completion of PEP course of antiviral drugs†
No antiviral drugs 198 81 (40.9) 1
Not completed 51 14 (27.5) 0.44 (0.17–1.15)
Completed 294 62 (21.1) 0.38 (0.22–0.65)
Seasonal Influenza vaccine
No 216 66 (30.6) 1
Yes 425 161 (37.9) 1.35 (0.95–1.92)

*Categories in which the response was missing or unknown are shown in the Table A1. ARI, acute respiratory infection; CI, confidence interval; PEP, postexposure prophylaxis.
†Excluding those who reported taking the treatment dose of antiviral drugs.

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