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Volume 17, Number 9—September 2011

Research

Role of Chlamydia trachomatis in Miscarriage

David Baud, Genevieve Goy, Katia Jaton, Maria-Chiara Osterheld, Serafin Blumer, Nicole Borel, Yvan Vial, Patrick Hohlfeld, Andreas Pospischil, and Gilbert GreubComments to Author 
Author affiliations: Author affiliations: University Hospital of Lausanne, Lausanne, Switzerland (D. Baud, G. Goy, K. Jaton, M.-C. Osterheld, Y. Vial, P. Hohlfeld, G. Greub); University of Zürich, Zürich, Switzerland (S. Blumer, N. Borel, A. Pospischil)

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Table 2

Clinical history and serologic, PCR, and IHC results of 8 women with samples positive for Chlamydia trachomatis by real-time PCR, University Hospital of Lausanne, Lausanne, Switzerland, November 2006–June 2009*

Study group, patient no.
No. pregnancies
Parity
Pregnancy, wk
C. trachomatis PCR
Placental histology
IgG
IgA
Placenta PCR
Vagina PCR
IHC
Miscarriage group
235 2 0 8 + + + + Lymphocytes in chorion, acute endometritis
355 1 0 7 + + + Polymorphonuclear cells in decidua
518 2 0 6 + + + + Subchorial fibrin, lymphocytes in decidua
564 5 2 12 + + + + + Lymphocytes in decidua
568 2 1 6 - + Lymphocytes in decidua, hemorrhagic necrosis
460
1
0
11
+
+

+
+
Presence of eosinophils
Control group
35 2† 1 37 + + + Histiocytes, rare calcifications
390 1 1 40 + + + + Chronic deciduitis

*Ig, immunoglobulin; IHC, Immunohistochemical analysis; +, positive; –, negative.
†One previous termination of pregnancy.

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