Central Venous Catheter–associated Nocardia Bacteremia in Cancer Patients
Fadi Al Akhrass, Ray Hachem, Jamal A. Mohamed, Jeffrey Tarrand, Dimitrios P. Kontoyiannis, Jyotsna Chandra, Mahmoud Ghannoum, Souha Haydoura, Ann Marie Chaftari, and Issam Raad
Author affiliations: Author affiliations: The University of Texas MD Anderson Cancer Center, Houston, Texas, USA (F. Al Akhrass, R. Hachem, J.A. Mohamed, J. Tarrand, D.P. Kontoyiannis, A.M. Chaftari, I. Raad); Case Western Reserve University, Cleveland, Ohio, USA (J. Chandra, M. Ghannoum); University Hospitals Case Medical Center, Cleveland (J. Chandra, M. Ghannoum); Kansas University School of Medicine, Wichita, Kansas, USA (S. Haydoura)
Figure 4. Scanning electron microscopy of Nocardia spp. biofilm on silicone central venous catheters. A) N. nova complex (disseminated Nocardia bacteremia) on the surface, showing heavy biofilm matrix covering filamentous cells. B) N. nova complex (definite central line–associated bloodstream infection) showing network of filamentous (thin arrow), partially covered with opaque biofilm matrix (thick arrows). Original magnifications ×2,500.
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