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Volume 17, Number 9—September 2011
Letter

Highly Virulent Escherichia coli O26, Scotland

Kevin G.J. PollockComments to Author , Sheetal Bhojani, T. James Beattie, Lesley Allison, Mary Hanson, Mary E. Locking, and John M. Cowden
Author affiliations: Author affiliations: Health Protection Scotland, Glasgow, Scotland (K.G.J. Pollock, M.E. Locking, J.M. Cowden); Yorkhill Hospital, Glasgow (T.J. Beattie, S. Bhojani); Scottish E. coli O157/VTEC Reference Laboratory, Edinburgh, Scotland (L. Allison, M. Hanson)

Main Article

Table

Characteristics of infection in children with Escherichia coli O157 versus E. coli O26, Scotland, 2010*

Variable O157 HUS, n = 12 O26 HUS, n = 3 p value
Age, y
4.5 ± 1.0
3.7 ± 1.3

Clinical signs and symptoms
Diarrhea 12 3
Bloody diarrhea 8 (67) 2 (67) NS
Abdominal pain 8 (67) 3 (75) NS
Fever 2 (17) 1 (33) NS
Neurologic involvement 3 (25) 3 (100) 0.02
Diabetes 1 (12) 2 (67) 0.02
Cardiomyopathy 0 1 (33) 0.04
Anuria, d
7.7 ± 2.4
15.7 ± 1.3
0.04
Clinical parameters
Leukocyte count × 109/L 42.1 ± 14.4 25.9 ± 4.8 NS
C-reactive protein, mg/L 93.5 ± 28.4 151 ± 74 NS
Serum albumin, g/L 22.5 ± 1.3 22.3 ± 2.4 NS
Lactate dehydrogenase, IU/L
2,521 ± 362
1,991 ± 642
NS
Admission to ITU 3 (25) 3 (100) 0.04
Duration of hospitalization, d
13.2 ± 2.2
25 ± 3.8
0.03
Treatment
Peritoneal dialysis, d 7.4 ± 1.9 10 NS
Hemodialysis, d 8.5 ± 1.5 8.3 ± 3.0 NS
Hemofiltration 0 3 (100) 0.001
Laparotomy
0
1 (33)
0.04
Postdischarge hypertension 0 2 (67) 0.01

*Values are mean ± SE or no. (%). Significance relates to difference between groups. HUS, hemolytic uremic syndrome; NS, not significant, ITU, intensive treatment unit.

Main Article

Page created: September 06, 2011
Page updated: September 06, 2011
Page reviewed: September 06, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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