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Volume 18, Number 1—January 2012

Research

High Prevalence of Multidrug-Resistant Tuberculosis, Swaziland, 2009–2010

Elisabeth Sanchez-PadillaComments to Author , Themba Dlamini, Alexandra Ascorra, Sabine Rüsch-Gerdes, Zerihun Demissie Tefera, Philippe Calain, Roberto de la Tour, Frauke Jochims, Elvira Richter, and Maryline Bonnet
Author affiliations: Epicentre, Paris, France (E. Sanchez-Padilla, A. Ascorra, M. Bonnet); National Tuberculosis Control Programme, Mbabane, Swaziland (T. Dlamini); National Reference Center for Mycobacteria, Borstel, Germany (S. Rüsch-Gerdes, E. Richter); Médecins Sans Frontières, Geneva, Switzerland (Z.D. Tefera, P. Calain, R. de la Tour, F. Jochims)

Main Article

Table 1

Baseline characteristics of case-patients in a study of MDR TB, Swaziland, 2009–2010*

Characteristic New, n = 420 Previously treated, n = 420 Total, n = 840
Median age, y 32 (IQR 26–40) 33 (IQR 28–43) 33 (IQR 27–41)
Sex
  M 206 (49.0) 196 (46.7) 402 (47.9)
  F 214 (51.0) 224 (53.3) 438 (52.1)
Region of residence
  Shiselweni 106 (25.2) 96 (22.9) 202 (24.0)
  Manzini 106 (25.2) 119 (28.3) 225 (26.8)
  HhoHho 120 (28.6) 109 (26.0) 229 (27.3)
  Lubombo 86 (20.5) 96 (22.9) 182 (21.7)
  Unknown 2 (0.5) 0 2 (0.2)
Education
  None 97 (23.1) 75 (17.9) 172 (20.5)
  Primary school 144 (34.3) 145 (34.5) 289 (34.4)
  Secondary school 104 (24.8) 112 (26.7) 216 (25.7)
  High school 62 (14.8) 56 (13.3) 118 (14.0)
  Tertiary 10 (2.4) 19 (4.5) 29 (3.5)
  Unknown 3 (0.7) 13 (3.1) 16 (1.9)
Employment (permanent job)
  No 285 (67.9) 293 (69.8) 578 (68.8)
  Yes 127 (30.2) 115 (27.4) 242 (28.8)
  Unknown 8 (1.9) 12 (2.9) 20 (2.4)
HIV-positive status known 279/316 (77.3) 327/397 (82.4) 606/758 (79.9)
Previous anti-TB treatment courses
  1 352 (83.8)
  2 39 (9.3)
  >2 14 (3.3)
  Unknown 15 (3.6)
Previous TB treatment regimen
  Category I 349 (83.1)
  Category II 60 (14.3)
  MDR 3 (0.7)
  Other 8 (1.9)
Outcome of most recent TB treatment
  Cured 76 (18.1)
  Completed 158 (37.6)
  Failed category I 109 (26.0)
  Failed category II 11 (2.6)
  Defaulted 45 (10.7)
  Unknown 21 (5.0)

*Values are no. (%) or no. positive/no. tested (%) unless otherwise indicated. MDR, multidrug resistant; TB, tuberculosis; IQR, interquartile range.

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