Lack of Cross-protection against Bordetella holmesii after Pertussis Vaccination
Figure 4. . . . Comparison of splenic interferon (IFN)–γ (A) and interleukin (IL)–10 (B) responses in naive mice versus mice vaccinated with whole-cell Bordetella holmesii vaccine (wH), whole-cell pertussis vaccine (wP), and acelullar pertussis vaccine (aP). Splenocytes from naive mice or wH-, wP-, or aP-vaccinated mice were stimulated with media only or media containing heat-killed B. pertussis (B.p.), B. parapertussis (B.p.p.), or B. holmesii (B.h.). Error bars indicate SE.