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Volume 18, Number 11—November 2012

Research

Lack of Cross-protection against Bordetella holmesii after Pertussis Vaccination

Xuqing Zhang, Laura S. Weyrich, Jennie S. Lavine, Alexia T. Karanikas, and Eric T. HarvillComments to Author 
Author affiliations: The Pennsylvania State University, University Park, Pennsylvania, USA

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Figure 4

Comparison of splenic interferon (IFN)–γ (A) and interleukin (IL)–10 (B) responses in naive mice versus mice vaccinated with whole-cell pertussis vaccine (wP), aceullar pertussis vaccine (aP), and whole-cell Bordetella holmesii vaccine (wH). Splenocytes from naive mice or wH-, wP-, or aP-vaccinated mice were stimulated with media only or media containing heat-killed B. pertussis (B.p.), B. parapertussis (B.p.p.), or B. holmesii (B.h.). Error bars indicate SE.

Figure 4. . . . Comparison of splenic interferon (IFN)–γ (A) and interleukin (IL)–10 (B) responses in naive mice versus mice vaccinated with whole-cell Bordetella holmesii vaccine (wH), whole-cell pertussis vaccine (wP), and acelullar pertussis vaccine (aP). Splenocytes from naive mice or wH-, wP-, or aP-vaccinated mice were stimulated with media only or media containing heat-killed B. pertussis (B.p.), B. parapertussis (B.p.p.), or B. holmesii (B.h.). Error bars indicate SE.

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