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Volume 18, Number 11—November 2012

Research

Lack of Cross-protection against Bordetella holmesii after Pertussis Vaccination

Xuqing Zhang, Laura S. Weyrich, Jennie S. Lavine, Alexia T. Karanikas, and Eric T. HarvillComments to Author 
Author affiliations: The Pennsylvania State University, University Park, Pennsylvania, USA

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Figure 5

Antibody responses to whole-cell pertussis vaccine (wP), aceullar pertussis vaccine (aP), and whole-cell Bordetella holmesii vaccine (wH). A) Specific Ig titers of serum antibodies for B. pertussis (B.p.), B. parapertussis (B.p.p.), or B. holmesii (B.h.) for wH-, wP- or aP- vaccinated mice. Error bars indicate SE. *p<0.01. B) Western blots of B. pertussis, B. parapertussis, and B. holmesii lysates probed with naive serum or wH-, wP-, or aP-induced serum.

Figure 5. . . . Antibody responses to whole-cell pertussis vaccine (wP), aceullar pertussis vaccine (aP), and whole-cell Bordetella holmesii vaccine (wH). A) Specific Ig titers of serum antibodies for B. pertussis (B.p.), B. parapertussis (B.p.p.), or B. holmesii (B.h.) for wH-, wP- or aP- vaccinated mice. Error bars indicate SE. *p<0.01. B) Western blots of B. pertussis (1), B. parapertussis (2), and B. holmesii (3) lysates probed with naive serum or wH-, wP-, or aP-induced serum (IS).

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