Emerging Infectious Disease ISSN: 1080-6059

Mycoplasmosis in Ferrets

Matti Kiupel

, Danielle R. Desjardins, Ailam Lim, Carole Bolin, Cathy A. Johnson-Delaney, James H. Resau, Michael M. Garner, and Steven R. Bolin

Author affiliations: Michigan State University, Lansing, Michigan, USA (M. Kiupel, D.R. Desjardins, A. Lim, C. Bolin, S.R. Bolin); Eastside Avian and Exotic Animal Medical Center, Kirkland, Washington, USA (C.A. Johnson-Delaney); Van Andel Research Institute, Grand Rapids, Michigan, USA (J.H. Resau); and Northwest ZooPath, Monroe, Washington, USA (M.M. Garner)

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Figure 3

Micrographs of a section of lung from a 2-year-old ferret that died of acute dyspnea. A) Image shows moderate bronchointerstitial pneumonia with severe hyperplasia of bronchiole-associated lymphoid tissue around a narrowed airway lumen; magnification ×4. B) Immunohistochemical analysis conducted with antibodies against mycoplasmas demonstrates intense labeling along the apical border of the ciliated respiratory epithelium; magnification ×40. C) Confocal scanning laser microscopy conducted with a

Figure 3. . . Micrographs of a section of lung from a 2-year-old ferret that died of acute dyspnea. A) Image shows moderate bronchointerstitial pneumonia with severe hyperplasia of bronchiole-associated lymphoid tissue around a narrowed airway lumen; original magnification ×40. B) Immunohistochemical analysis conducted with antibodies against mycoplasmas demonstrates intense labeling along the apical border of the ciliated respiratory epithelium; original magnification ×40. C) Confocal scanning laser microscopy conducted with antibodies against mycoplasmas demonstrates intense fluorescent labeling along the brush border of the bronchial epithelial cells; original magnification ×40.

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