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Volume 18, Number 11—November 2012

Research

Community Outbreak of Adenovirus, Taiwan, 2011

Tsung-Pei Tsou1, Boon-Fatt Tan1, Hsin-Yu Chang1, Wan-Chin Chen, Yuan-Pin Huang, Chen-Yin Lai, Yen-Nan Chao, Sung-Hsi Wei, Min-Nan Hung, Li-Ching Hsu, Chun-Yi Lu, Pei-Lan Shao, Jung-Jung Mu, Luan-Yin Chang, Ming-Tsan LiuComments to Author , Li-Min Huang, and The Unknown Pathogen Discovery/Investigation Group
Author affiliations: Centers for Disease Control, Taipei, Taiwan (T.P. Tsou, W.C. Chen, Y.P. Huang, Y.N. Chao, S.H. Wei, M.N. Hung, L.C. Hsu, J.J. Mu, M.T. Liu); and National Taiwan University Hospital, Taipei (B.F. Tan, H.Y. Chang, C.Y. Lai, C.Y. Lu, P.L. Shao, L.Y. Chang, L.M. Huang)

Main Article

Table 1

Characteristics of 202 children hospitalized for adenovirus infection at National Taiwan University Hospital, by disease severity, Taipei City, Taiwan, November 2010–June 2011*

Characteristic All Severe infection, n = 31 Nonsevere infection, n = 171 p value
Median age, mo (range) 40 (1–189) 36 (1–185) 41 (2–189) 0.287
Male sex 115 (57) 21 (68) 94 (55) 0.186
Contact history 119 (59) 15 (48) 104 (61) 0.196
Median hospitalization, d (range) 5 (1–126) 18 (4–126) 5 (1–44) <0.001
Death rate 7 (4) 7 (23) 0 (0) <0.001
Any underlying disease 76 (38) 24 (77) 52 (30) <0.001

Prematurity

36 (18) 8 (26) 28 (16) 0.207

Cardiopulmonary†

31 (15) 12 (39) 19 (11) <0.001

Neurologic‡

25 (12) 19 (61) 6 (4) <0.001

Hematologic§

2 (1) 1 (3) 1 (0.6) 0.284

Metabolic¶

7 (4) 4 (13) 3 (2) 0.012

Immunodeficiency#

1 (0.5) 1 (3) 0 (0) 0.153

*Values are no. (%) patients except as indicated. Severe infection indicates patients who were admitted to the intensive care unit.
†Congenital heart diseases (12), asthma (11), chronic lung disease (4), tracheobronchial stenosis (2), and laryngo-tracheo-bronchomalacia (2).
‡Cerebral palsy, epilepsy, and psychomotor retardation.
§Acute myeloid leukemia and Burkitt’s leukemia.
¶Pompe disease, metachromatic leukodystrophy, glycogen storage disease, isovaleric acidemia, short-chain acyl-coA dehydrogenase deficiency, renal tubular acidosis, and mitochondrial disease.
#Hypogammaglobulinemia.

Main Article

1These authors contributed equally to this article.

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