Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 18, Number 11—November 2012

Dispatch

Seroprevalence of Influenza A(H1N1)pdm09 Virus Antibody, England, 2010 and 2011

Katja HoschlerComments to Author , Catherine Thompson, Nick Andrews, Monica Galiano, Richard Pebody, Joanna Ellis, Elaine Stanford, Marc Baguelin, Elizabeth Miller, and Maria Zambon
Author affiliations: Health Protection Agency, London, UK (K. Hoschler, C. Thompson, N. Andrews, M. Galiano, R. Pebody; J. Ellis, M. Baguelin, E Miller, M. Zambon); and Health Protection Agency, Manchester, UK (E. Stanford)

Main Article

Table 1

Seroprevalence of influenza A(H1N1)pdm09 virus antibody, England, 2010 and 2011*

Characteristic No. seropositive samples/no. total samples† (% seropositive samples, 95% CI)
Post–second wave‡
Pre–third
Post–third wave
HI MN HI MN HI MN
Age group, y

<5

36/98 (0.37, 0.27–0.47) 31/77 (0.4, 0.29–0.52) 94/182 (0.52, 0.44–0.59) 88/174 (0.51, 0.43–0.58) 99/160 (0.62, 0.54–0.69) 93/150 (0.62, 0.54–0.7)

5–14

132/213 (0.62, 0.55–0.69) 69/107 (0.64, 0.55–0.73) 142/244 (0.58, 0.52–0.64) 152/237 (0.64, 0.58–0.7) 155/200 (0.78, 0.71–0.83) 146/199 (0.73, 0.67–0.79)

15–24

68/154 (0.44, 0.36–0.52) 44/101 (0.44, 0.34–0.54) 152/405 (0.38, 0.33–0.42) 156/400 (0.39, 0.34–0.44) 216/320 (0.68, 0.62–0.73) 188/311 (0.6, 0.55–0.66)

25–44

66/200
(0.33, 0.27–0.4) 31/83 (0.37, 0.27–0.49) 106/370 (0.29, 0.24–0.34) 114/370 (0.31, 0.26–0.36) 187/294 (0.64, 0.58–0.69) 155/283 (0.55, 0.49–0.61)

45–64

59/220 0.27, 0.21–0.33) 42/110 (0.38, 0.29–0.48) 69/320 (0.22, 0.17–0.26) 93/318 (0.29, 0.24–0.35) 62/138 (0.45, 0.36–0.54) 52/135 (0.39, 0.3–0.47)

65–74

36/145
(0.25, 0.18–0.33) 27/87 (0.31, 0.22–0.42) 35/168 (0.21, 0.15–0.28) 42/167 (0.25, 0.19–0.32) 38/74 (0.51, 0.39–0.63) 38/74 (0.51, 0.39–0.63)

>75

55/172 (0.32, 0.25–0.4) 77/163 (0.47, 0.39–0.55) 16/93 (0.17, 0.1–0.26) 25/92 (0.27, 0.18–0.37) 46/71 (0.65, 0.53–0.76) 39/71 (0.55, 0.43–0.67)
Region§

Total

1,202 1,782 1,257

North West

561 624 337

South West

404 232 265

North East

237 526 179

East

0 292 122

Yorkshire and 
Humber

0 108 354

*HI, hemagglutination inhibition assay; MN, microneutralization assay.
†Samples with titers >32 by HI or >40 by MN,
‡For data consistency, samples from only North West, South West, and North East regions were included in this analysis because these regions also were among the 5 regions in pre– and post–third wave samples.
§Numbers by region describe total available number of samples (all analyzed at least by HI assay).

Main Article

TOP