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Volume 18, Number 2—February 2012
CME ACTIVITY - Research

Invasive Pneumococcal Disease and Pandemic (H1N1) 2009, Denver, Colorado, USA

George E. NelsonComments to Author , Kenneth A. Gershman, David L. Swerdlow, Bernard W. Beall, and Matthew R. Moore
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (G.E. Nelson, D.L. Swerdlow, B.W. Beall, M.R. Moore); Colorado Department of Health and the Environment, Denver, Colorado, USA (K.A. Gershman)

Main Article

Table 1

Epidemiologic characteristics of patients with invasive pneumococcal disease, Denver, Colorado, USA, February and October 2009*

Characteristic Patients with pandemic (H1N1) 2009, Oct 2009, n = 58 Patients with seasonal influenza, Feb 2009, n = 45 p value
Age, y
0–<5 6 (10) 0 (0) NC
5–19 3 (5) 3 (7) NC
20–39 10 (17) 6 (13) NC
40–59 26 (45) 17 (38) NC
>60 13 (22) 19 (42) NC
Median age (range 2 mo–91 y) 45 54 0.02
Sex 0.120
M 38 (66) 26 (58) NC
F 20 (34) 16 (36) NC
Unknown 0 3 (7) NC
Race† 0.012
White 31 (53) 11 (24) NC
African American 4 (7) 3 (7) NC
Asian 0 (0) 2 (4) NC
Unknown 23 (40) 29 (64) NC
Ethnicity† <0.0001
Hispanic 14 (24) 7 (16) NC
Non-Hispanic 25 (43) 4 (9) NC
Unknown 19 (33) 34 (76) NC
Concurrent condition‡ NC
Any 40 (69) 17 (38) <0.0001
Chronic lung disease 17 (29) 3 (7) 0.0002
Diabetes 5 (9) 6 (13) 0.852
HIV infection 2 (3) 0 (0) 0.247
Liver disease 5 (8.6) 2 (4) 0.276
Smoking 15 (26) 10 (22) 0.669
Hospitalized
Yes 54 (93) 36 (80) 0.536
No 4 (7) 2(4) NC
Unknown 0 7 (16) NC
Tested for influenza§ 47 (81) NA NC
Outpatient setting 8 NA NC
Inpatient setting 43 NA NC
Positive test result for influenza§ 10 NA NC

*Values are no. (%) unless otherwise indicated. NA, not available; NC, not calculated.
†Race and ethnicity data required additional patient consent.
‡Underlying concurrent condition comparisons were adjusted for age.
§Includes data from supplemental case report form not available for prior years.

Main Article

Page created: January 26, 2012
Page updated: January 26, 2012
Page reviewed: January 26, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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