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Volume 18, Number 3—March 2012

Research

Lineage-specific Virulence Determinants of Haemophilus influenzae Biogroup aegyptius

Fiona R. Strouts1, Peter Power, Nicholas J. Croucher, Nicola Corton, Andries van Tonder, Michael A. Quail, Paul R. Langford, Michael J. Hudson, Julian Parkhill, J. Simon KrollComments to Author , and Stephen D. Bentley
Author affiliations: Imperial College London, London, UK (F.R. Strouts, P.R. Langford, J.S. Kroll); University of Oxford, Oxford, UK (P. Power); Wellcome Trust Sanger Institute, Cambridge, UK (N.J. Croucher, N. Corton, A. van Tonder, M.A. Quail, J. Parkhill, S.D. Bentley); The Health Protection Agency, Salisbury, UK (M.J. Hudson)

Main Article

Figure 7

Comparison of the cha locus from Haemophilus cryptic genospecies strain 1595 to the TabA1 locus in the Brazilian purpuric fever (BPF) clone of H. influenzae biogroup aegyptius (HaeBPF) F3031 and the TahA1 locus in H. influenzae biogroup aegyptius (Hae) conjunctivitis (CON) F3047. Strain F3031 includes an additional 2 coding sequences downstream of tabA1, HIBPF06250 and IS1016, that are absent from strain F3047. HIBPF06250 is a conserved hypothetical protein with homology (62% aa identity) to the

Figure 7. Comparison of the cha locus from Haemophilus cryptic genospecies strain 1595 to the TabA1 locus in the Brazilian purpuric fever (BPF) clone of H. influenzae biogroup aegyptius (HaeBPF) F3031 and the TahA1 locus in H. influenzae biogroup aegyptius (Hae) conjunctivitis (CON) F3047. Strain F3031 includes an additional 2 coding sequences downstream of tabA1, HIBPF06250 and IS1016, that are absent from strain F3047. HIBPF06250 is a conserved hypothetical protein with homology (62% aa identity) to the 2 coding sequences located directly downstream of cha that share 69% aa identity with each other.

Main Article

1Current affiliation: Stanford University, Palo Alto, California, USA.

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