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Volume 18, Number 3—March 2012

Research

Using Genotyping and Geospatial Scanning to Estimate Recent Mycobacterium tuberculosis Transmission, United States

Patrick K. MoonanComments to Author , Smita Ghosh, John E. Oeltmann, J. Steven Kammerer, Lauren S. Cowan, and Thomas R. Navin
Author affiliations: US Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Table 2

Demographic, behavioral, and clinical characteristics of persons involved in putative recent TB transmission events, by location, United States, 2005–2009*

US Census region, no. (%) persons,† and main characteristics Odds ratio (99% CI) Wald p value
West, 11,550 (31.3)
    Mycobacterium bovis TB 4.4 (2.2–8.8) <0.0001
    US-born 2.4 (4.3–4.7) <0.0001
    East-Asian phylogenetic lineage TB 2.4 (1.4–4.2) <0.0001
    Hispanic 2.3 (1.7–3.0) <0.0001
    Homeless‡ 1.9 (1.5–2.9) <0.0001
Midwest, 10,502 (28.5)
    US-born 2.5 (2.1–3.1) <0.0001
    Black, non-Hispanic 2.1 (1.7–2.6) <0.0001
    Substance abuser§ 1.4 (1.3–1.6) <0.0001
Northeast, 6,090 (16.5)
    Hispanic 2.1 (1.5–3.0) <0.0001
    East-Asian phylogenetic lineage TB 2.0 (1.1–3.6) 0.001
    US-born 1.6 (1.2–2.1) <0.0001
    Substance abuser§ 1.6 (1.2–2.1) <0.0001
South 8,718 (23.7)
    Black, non-Hispanic 3.6 (1.5–8.6) <0.0001
    US-born 3.2 (2.5–4.2) <0.0001
    Euro-American phylogenetic lineage TB 2.2 (1.1, 4.3) 0.004
    Substance abuser§ 1.5 (1.1–4.3) <0.0001
Total, 36,860

*TB, tuberculosis.
†Column percentage.
‡Self-reported homelessness within 12 mo preceding TB diagnosis.
§Self-reported excess alcohol consumption, injection drug use, or noninjection drug use within 12 mo preceding TB diagnosis.

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