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Volume 18, Number 4—April 2012

Letter

Methicillin-Susceptible Staphylococcus aureus ST398, New York and New Jersey, USA

José R. Mediavilla, Liang Chen, Anne-Catrin Uhlemann, Blake M. Hanson, Marnie Rosenthal, Kathryn Stanak, Brian Koll, Bettina C. Fries, Donna Armellino, Mary Ellen Schilling, Don Weiss, Tara C. Smith, Franklin D. Lowy, and Barry N. KreiswirthComments to Author 
Author affiliations: University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA (J.R. Mediavilla, L. Chen, B.N. Kreiswirth); Columbia University, New York, New York, USA (A.-C. Uhlemann, F.D. Lowy); University of Iowa, Iowa City, Iowa, USA (B.M. Hanson, T.C. Smith); Jersey Shore University Medical Center, Neptune, New Jersey, USA (M. Rosenthal); Beth Israel Medical Center, New York (K. Stanak, B. Koll); Albert Einstein College of Medicine, Bronx, New York, USA (B.C. Fries); North Shore University Hospital, Manhasset, New York, USA (D. Armellino, M.E. Schilling); New York City Department of Health and Mental Hygiene, New York (D. Weiss)

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Table

Characteristics of Staphylococcus aureus clonal complex 398 isolates, New York and New Jersey, USA, 2004–2010*

Isolate† Year Geographic location‡ Submitting institution§ Isolate source Antimicrobial resistance PFGE pattern spa type spa repeats Ridom type ST
BK13684 2004 Monmouth County, NJ Laboratory A Wound PEN – 539 XKAOAOBQO t034 398
BK18505 2006 Manhattan Laboratory A Wound – A1 109 XKAOAOBO t571 398
BK21466 2007 Staten Island Laboratory A Arm, face, leg, buttocks – A2 109 XKAOAOBO t571 398
BK21732 2007 Manhattan Laboratory A Genital PEN, CLI, ERY A3 109 XKAOAOBO t571 398
BK27037 2007 The Bronx Hospital A Blood, lung abscess PEN, CLI, ERY A4 109 XKAOAOBO t571 398
BK23527 2008 Manhattan Hospital B Blood, buttocks PEN, ERY, OXA – 109 XKAOAOBO t571 398
BK26722 2009 Manhattan Hospital B Blood CLI, ERY A1 109 XKAOAOBO t571 398
BK31274 2010 Nassau County, NY Hospital C Blood, sternum PEN, CLI, ERY A1 1376 XKAOBO t1451 398
BK13771 2004 Somerset County, NJ Laboratory A Wound PEN, ERY B4 716 XKBBM t2993 291
BK13451 2004 Union County, NJ Laboratory A Wound PEN B2 718 XKBQBMM t1149 291
BK19382 2006 Staten Island Laboratory A Right ear PEN B1 865 XKBQBBM t2313 291
BK21746 2007 Manhattan Laboratory A Torso PEN, ERY B1 208 XKBQBBMM t937 291
BK22183 2007 Manhattan Laboratory A Axilla PEN B3 208 XKBQBBMM t937 291

*Antimicrobial drug susceptibilities were obtained from submitting institutions (unavailable for BK18505 and BK21466). PFGE was performed by using Cfr9I, with patterns assigned on the basis of 80% similarity cutoffs (BioNumerics version 6.5, Applied Maths, Austin, TX, USA); BK13684 and BK23527 were unavailable for PFGE analysis. spa typing was performed by using eGenomics software (www.egenomics.com), and Ridom spa types were assigned by using the SpaServer Web site (www.spaserver.ridom.de). Multilocus sequence typing was performed as described (http://saureus.mlst.net). PFGE, pulsed-field gel electrophoresis; spa, staphylococcal protein A; ST, sequence type; wound, skin and soft-tissue infections from unspecified body sites; PEN, penicillin; CLI, clindamycin; ERY, erythromycin; OXA, oxacillin (resistance >4 μg/mL was reported for BK23527, but mecA was not detected by real-time PCR).
†BK27037 has been described (7).
‡Manhattan, Staten Island, and the Bronx are boroughs of New York, New York.
§Laboratory A is a large outpatient commercial laboratory serving the metropolitan New York, New York, area.

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