Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 18, Number 5—May 2012
Research

Characterization of Virulent West Nile Virus Kunjin Strain, Australia, 2011

Melinda J. Frost1, Jing Zhang1, Judith H. Edmonds1, Natalie A. Prow1, Xingnian Gu, Rodney Davis, Christine Hornitzky, Kathleen E. Arzey, Deborah Finlaison, Paul Hick, Andrew Read, Jody Hobson-Peters, Fiona J. May, Stephen L. Doggett, John Haniotis, Richard C. Russell, Roy A. Hall2, Alexander A. Khromykh2, and Peter D. Kirkland2Comments to Author 
Author affiliations: Elizabeth Macarthur Agriculture Institute, Menangle, New South Wales, Australia (M.J. Frost, J. Zhang, X. Gu, R. Davis, C. Hornitzky, K.E. Arzey, D. Finlaison, P. Hick, A. Read, P.D. Kirkland); The University of Queensland, St Lucia, Queensland, Australia (J.H. Edmonds, N.A Prow, J. Hobson-Peters, F.J. May, R.A. Hall, A. A. Khromykh); University of Sydney and Westmead Hospital, Westmead, New South Wales, Australia (S.L. Doggett, J. Haniotis, R.C. Russell)

Main Article

Table 4

Virulence of 3 WNVs in 18- to19-day-old mice after intraperitoneal injection, Australia, 2011*

Virus and dose, PFU No. mice/no. died Average survival time, d LD50
WNVNY99      
100 10/10 6.1  
10 10/10 6.7  
1 10/10 6.9 0.1 PFU
0.1 5/10 7.8  
WNVKUN      
1,000 9/10 8.4  
100 4/10 8 13.4 PFU
10 6/10 10.2  
1 3/10 12  
WNVNSW2011      
1,000 10/10 7.1  
100 10/10 7.4  
10 10/10 7.7 0.5 PFU
1 7/10 8.3  
0.1 1/10 10  

*WNV, West Nile virus; LD50, dose at which 50% of the mice died; NY, New York; KUN, Kunjin; NSW, New South Wales.

Main Article

1These authors contributed equally to the major technical aspects of this research.

2These authors served as joint senior authors.

Page created: April 12, 2012
Page updated: April 12, 2012
Page reviewed: April 12, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external