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Volume 18, Number 5—May 2012

CME ACTIVITY

Invasive Haemophilus influenzae Serotype e and f Disease, England and Wales

Shamez N. LadhaniComments to Author , Sarah Collins, Anna Vickers, David J. Litt, Carina Crawford, Mary E. Ramsay, and Mary P.E. Slack
Author affiliations: Health Protection Agency, London, UK (S.N. Ladhani, S. Collins, A. Vickers, D.J. Litt, C. Crawford, M.E. Ramsay, M.P.E. Slack); St. George’s University of London, London (S.N. Ladhani)

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Figure 4

Minimum spanning tree showing the relationship between multilocus sequence types of 33 Haemophilus influenzae serotype e (Hie, red) and 99 Hif (green) strains isolated from patients in England and Wales, 2009–2010. The tree was derived from the 7 multilocus sequence type alleles of each isolate; the number within each circle represents a unique sequence type, and the size of the circle illustrates the proportion of strains with that sequence type (the smallest circle represents 1 isolate). Thick

Figure 4. . . Minimum spanning tree showing the relationship between multilocus sequence types of 33 Haemophilus influenzae serotype e (Hie, red) and 99 Hif (green) strains isolated from patients in England and Wales, 2009–2010. The tree was derived from the 7 multilocus sequence type alleles of each isolate; the number within each circle represents a unique sequence type, and the size of the circle illustrates the proportion of strains with that sequence type (the smallest circle represents 1 isolate). Thick lines, thin lines, and dotted lines separating circles indicate single-, double-, and triple-locus variants, respectively.

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