Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 18, Number 6—June 2012

Letter

Pneumococcal Serotype–specific Unresponsiveness in Vaccinated Child with Cochlear Implant

Elaine Stanford, Shamez LadhaniComments to Author , Mary Slack, David Scott, Alec Fitzgerald-O’Connor, Pauline Waight, Rashmi Malkani, and Ray Borrow
Author affiliations: Health Protection Agency, Manchester, UK (E. Stanford, R. Borrow); Health Protection Agency, London, UK (S. Ladhani, M. Slack, P. Waight, R. Malkani); East Sussex Hospitals National Health Service Trust, Conquest Hospital, St Leonards-on-Sea, UK (D. Scott); St Thomas’ Hospital London, London (A. Fitzgerald-O’Connor); University of Manchester, Manchester (R. Borrow)

Main Article

Table

. Pneumococcal serotype-specific IgG concentrations in 2-year-old child with recurrent pneumococcal meningitis, United Kingdom*

Patient age, mo Event Serotype-specific IgG, µg/mL
4 6B 9V 14 18C 19F 23F
1.9 PCV7 dose 1
3.9 PCV7 dose 2
13.4 PCV7 dose 3
22.8 Cochlear implant
23.4 Pneumococcal meningitis (episode 1)
24.4 PCV7 dose 4
25.6 Pneumococcal serologic testing 0.12 27.6 23.0 36.9 13.8 57.0 41.1
27.8 PPV23 dose 1
28.8 Pneumococcal serologic testing 0.18 14.2 13.1 30.4 11.4 11.7 32.0
32.0 Pneumococcal meningitis (episode 2)
35.1 PCV7 dose 5
36.1 Pneumococcal serologic testing 0.20 18.40 7.12 12.50 12.40 2.78 37.1
39.0 PCR positive nasopharyngeal swab specimen for Streptococcus pneumoniae serotype 4

*PCV7, 7-valent pneumococcal conjugate vaccine; PPV23, 23-valent pneumococcal polysaccharide vaccine. Blank spaces indicate not tested.

Main Article

TOP