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Volume 18, Number 6—June 2012
Research

Intrafamilial Circulation of Tropheryma whipplei, France

Florence Fenollar, Alpha K. Keita, Sylvain Buffet, and Didier RaoultComments to Author 
Author affiliations: Université de la Méditerranée, Marseille, France

Main Article

Table A1

Results of Tropheryma whipplei Western blot serologic analysis for 30 relatives of 2 T. whipplei carriers, 8 patients with classic Whipple disease, and 3 patients with localized infections and their T. whipplei PCR results, France, 2003–2011*

Infection status
Age, y/sex
Immune response
Relative, T. whipplei PCR results, and immune response
Relative 1
Relative 2
Relative 3
Relative 4
Relative 5
Relationship/age, y
Feces/saliva/ immune response
Relationship/age, y
Feces/saliva/immune response
Relationship/age, y
Feces/saliva/immune response
Relationship/age, y
Feces/saliva/immune response
Relationship/age, y
Feces/saliva/immune response
Carrier
Carrier 1 47/M Strong Wife/41 +/–/strong Son 1/12 +/+/strong Son 2/12 +/–/strong
Carrier 2 35/M Strong Wife/29 +/–/strong -
Classic Whipple disease
Patient 1 40/F Deficient Father/71 +/+/strong Mother/70 +/–/strong
Patient 2 58/M Deficient Wife/60 –/–/strong Daughter/32 +/+/strong
Patient 3 48/M Deficient Wife/51 +/–/strong Son/22 +/–/strong
Patient 4 35/M Deficient Father/NA –/–/deficient Mother/NA –/–/deficient
Patient 5 26/F Deficient Father/57 –/–/strong Mother/55 +/–/strong
Patient 6 62/M Deficient Wife/62 –/–/strong
Patient 7 43/M Deficient Wife/45 –/–/deficient Son/20 +/+/deficient Daughter/18 +/–/deficient
Patient 8 75/M Deficient Wife/71 NA/–/strong -
Patient 9 39/F Deficient Husband/42 +/–/strong Brother/50 +/+/strong Mother/76 –/–/deficient Father/77 +/–/deficient Sister/52 +/–/strong
Localized infection
Patient 10 36/M Deficient Wife/43 NA/–/strong Son/12 NA/+/strong
Patient 11 71/F Deficient Husband/73 +/–/strong
Patient 12 55/F Strong Husband/53 –/–/strong Mother/75 –/–/strong Half aunt/56 –/NA/strong

*+, positive; –, negative; NA, not available. Blank cells indicate no additional relatives.

Main Article

Page created: May 11, 2012
Page updated: May 11, 2012
Page reviewed: May 11, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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