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Volume 18, Number 6—June 2012

Research

Intrafamilial Circulation of Tropheryma whipplei, France

Florence Fenollar, Alpha K. Keita, Sylvain Buffet, and Didier RaoultComments to Author 
Author affiliations: Université de la Méditerranée, Marseille, France

Main Article

Table A1

Results of Tropheryma whipplei Western blot serologic analysis for 30 relatives of 2 T. whipplei carriers, 8 patients with classic Whipple disease, and 3 patients with localized infections and their T. whipplei PCR results, France, 2003–2011*

Infection status
Age, y/sex
Immune response
Relative, T. whipplei PCR results, and immune response
Relative 1
Relative 2
Relative 3
Relative 4
Relative 5
Relationship/age, y
Feces/saliva/ immune response
Relationship/age, y
Feces/saliva/immune response
Relationship/age, y
Feces/saliva/immune response
Relationship/age, y
Feces/saliva/immune response
Relationship/age, y
Feces/saliva/immune response
Carrier
Carrier 1 47/M Strong Wife/41 +/–/strong Son 1/12 +/+/strong Son 2/12 +/–/strong
Carrier 2 35/M Strong Wife/29 +/–/strong -
Classic Whipple disease
Patient 1 40/F Deficient Father/71 +/+/strong Mother/70 +/–/strong
Patient 2 58/M Deficient Wife/60 –/–/strong Daughter/32 +/+/strong
Patient 3 48/M Deficient Wife/51 +/–/strong Son/22 +/–/strong
Patient 4 35/M Deficient Father/NA –/–/deficient Mother/NA –/–/deficient
Patient 5 26/F Deficient Father/57 –/–/strong Mother/55 +/–/strong
Patient 6 62/M Deficient Wife/62 –/–/strong
Patient 7 43/M Deficient Wife/45 –/–/deficient Son/20 +/+/deficient Daughter/18 +/–/deficient
Patient 8 75/M Deficient Wife/71 NA/–/strong -
Patient 9 39/F Deficient Husband/42 +/–/strong Brother/50 +/+/strong Mother/76 –/–/deficient Father/77 +/–/deficient Sister/52 +/–/strong
Localized infection
Patient 10 36/M Deficient Wife/43 NA/–/strong Son/12 NA/+/strong
Patient 11 71/F Deficient Husband/73 +/–/strong
Patient 12 55/F Strong Husband/53 –/–/strong Mother/75 –/–/strong Half aunt/56 –/NA/strong

*+, positive; –, negative; NA, not available. Blank cells indicate no additional relatives.

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