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Volume 18, Number 6—June 2012

Dispatch

Local Transmission of Imported Endemic Syphilis, Canada, 2011

Sergio FanellaComments to Author , Kamran Kadkhoda, Michelle Shuel, and Raymond Tsang
Author affiliations: University of Manitoba, Winnipeg, Manitoba, Canada (S. Fanella); Cadham Provincial Laboratory, Winnipeg (K. Kadkhoda); National Microbiology Laboratory, Winnipeg, (M. Shuel, R. Tsang)

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Table 2

Comparison of nucleotide sequences of tprI and tprC genes detected in clinical specimens from cases of endemic syphilis, Canada, 2011*

Strain† tprI gene sequence at nt positions 1740–1766, 5′ → 3′ GenBank accession no.
Clinical strain CTC CGA TGT TCC CTA CAT GGG CAT TGC JN674562
Bosnia A CTC CGA TGT TCC CTA CAT GGG CAT TGC DQ886678
Nichols‡ TGC TGA CGC TCC TTA CAT GGG TAT TGC NC_000919
Samoa D TGC TGA CGC TCC TTA CAT GGG TAT TGC DQ886680
tprC gene sequence at nt positions 1704–1736, 5′ → 3′
Clinical strain GGT GCT CTC CGA TGT TCC CTA CAT GGG CAT TGC JN674563
Bosnia A GGT GCT CTC CGA TGT TCC CTA CAT GGG CAT TGC DQ886673
Nichols‡ CGT GCT TGC TGA CGC TCC TTA CAT GGG CAT TGC NC_000919
Samoa D GGT GCT CTC CGA TGT TCC CTA CAT GGG TAT TAC DQ886671

*Boldface indicates differences in nucleotide sequences. BsrDI restriction sites are underlined.
†Sequences were obtained from GenBank: Bosnia A (T. pallidum subsp. endemicum), Samoa D (T. pallidum subsp. pertenue) and syphilis control strain Nichols (T. pallidum subsp. pallidum).
‡Sequence also confirmed in this study.

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