Figure 4. . . Neighbor-joining alignment of amino acid sequences for the fiber knob domains of macaque adenoviruses (5 representative members of simian adenovirus type B [SAdV-B]) and representative members from each human adenovirus (HAdV) species, with bootstrapping at 1,000 replicates. Alignment was performed by using CLC Bio version 6.1 software (CLC Bio, Aarhus, Denmark). Bootstrap values (percentages) are indicated on the nodes. SAdV-1 and SAdV-7 have been grouped together with HAdV-52 into HAdV-G; the other macaque adenoviruses (except for SAdV-18, SAdV-20, and the titi monkey adenovirus) have been grouped into SAdV-A and SAdV-B. Scale bar indicates number of substitutions per site.