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Volume 18, Number 7—July 2012

Research

Spike Protein Fusion Peptide and Feline Coronavirus Virulence

Hui-Wen Chang, Herman F. Egberink, Rebecca Halpin, David J. Spiro, and Peter J.M. RottierComments to Author 
Author affiliations: Utrecht University, Utrecht, the Netherlands (H.-W. Chang, H.F. Egberink, P.J.M. Rottier); and J. Craig Venter Institute, Rockville, Maryland, USA (R. Halpin, D.J. Spiro)

Main Article

Figure 1

Comparison of full genomes of 11 lethal feline infectious peritonitis viruses (FIPVs) with full genomes of 11 nonvirulent feline enteric coronaviruses (FECVs). Nucleotide (nt) positions are shown on the x-axis; y-axis indicates number of FIPV genomes for which the identity at the nt position differed from identity at same position in all FECV genomes. FIPV strain C1Je (GenBank accession no. DQ848678) was used as the reference for nt numbering. *Highest difference score: 9 FIPVs had identities at

Figure 1. . . Comparison of full genomes of 11 lethal feline infectious peritonitis viruses (FIPVs) with full genomes of 11 nonvirulent feline enteric coronaviruses (FECVs). Nucleotide (nt) positions are shown on the x-axis; y-axis indicates number of FIPV genomes for which the identity at the nt position differed from identity at same position in all FECV genomes. FIPV strain C1Je (GenBank accession no. DQ848678) was used as the reference for nt numbering. *Highest difference score: 9 FIPVs had identities at nt position 23531 that differed from those at the same position in all FECVs. 1a, gene 1a; 1b, gene 1b; S, spike protein gene; 3abc, gene cluster 3abc; E, envelope protein gene; M, membrane protein gene; N, nucleocapsid protein gene; 7ab, gene cluster 7ab.

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