Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 18, Number 8—August 2012

Research

Hepatitis E Virus Strains in Rabbits and Evidence of a Closely Related Strain in Humans, France

Jacques IzopetComments to Author , Martine Dubois, Stéphane Bertagnoli, Sébastien Lhomme, Stéphane Marchandeau, Samuel Boucher, Nassim Kamar, Florence Abravanel, and Jean-Luc Guérin
Author affiliations: Institut National de la Santé et de la Recherche Médicale, Toulouse, France (J. Izopet, M. Dubois, S. Lhomme, N. Kamar, F. Abravanel); Faculté de Médecine Toulouse-Purpan, Université Toulouse III Paul-Sabatier, Toulouse (J. Izopet, S. Lhomme, N. Kamar, F. Abravanel); Le Centre Hospitalier Universitaire de Toulouse, Toulouse (J. Izopet, M. Dubois, S. Lhomme, N. Kamar, F. Abravanel); École Nationale Vétérinaire de Toulouse, Toulouse (S. Bertagnoli, J.-L. Guérin); Office National de la Chasse et de la Faune Sauvage, Nantes, France (S. Marchandeau); and Labovet, Les Herbiers, France (S. Boucher )

Main Article

Table 3

Detection of HEV RNA by real time RT-PCR in the 12 wild rabbits from warren W3 according to tissue sampled, France*

Rabbit no. Liver
Intestine
Cecum
No. positive Mean viral load† No. positive Mean viral load† No. positive Mean viral load†
1 0 <LOD 0 <LOD 0 <LOD
2 0 <LOD 0 <LOD 0 <LOD
3 0 <LOD 0 <LOD 0 <LOD
4 3 7.3 3 5.3 2 3.4
5 3 3.7 1 3.1 0 <LOD
6 3 4.4 0 <LOD 0 <LOD
7 1 3.1 2 3.6 1 3.8
8 0 <LOD 0 <LOD 0 <LOD
9 3 6.6 3 5.2 3 4.6
10 0 <LOD 0 <LOD 0 <LOD
11 0 <LOD 0 <LOD 0 <LOD
12 3 3.7 2 3.6 1 3.8

*Three samples were obtained of each tissue type from each rabbit. HEV, hepatitis E virus; RT-PCR, reverse transcription PCR; LOD, limit of detection.
†log copies/g.

Main Article

TOP