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Volume 19, Number 1—January 2013

Research

Vaccination and Tick-borne Encephalitis, Central Europe

Franz X. HeinzComments to Author , Karin Stiasny, Heidemarie Holzmann, Marta Grgic-Vitek, Bohumir Kriz, Astrid Essl, and Michael Kundi
Author affiliations: Author affiliations: Medical University of Vienna, Vienna, Austria (F.X. Heinz, K. Stiasny, H. Holzmann, M. Kundi); National Institute of Public Health, Ljubljana, Slovenia (M. Grgic-Vitek); National Institute of Public Health, Prague, Czech Republic (B. Kriz); and GfK Austria Healthcare, Vienna (A. Essl)

Main Article

Table

Field effectiveness of TBE vaccination, Austria, 2000–2011*

Scenario, by age group, y Unvaccinated persons
Regularly vaccinated persons
Irregularly vaccinated persons
Incidence† Incidence† FE, % (95% CI) Incidence† FE, % (95% CI)
Best-case‡

0–14

1.62 0.10 94.0 (88.0–97.0) 0.18 88.6 (63.3–96.5)

15–50

5.41 0.02 99.7 (99.3–99.9) 0.26 95.3 (92.9–96.9)

51–60

7.60 0.13 98.2 (96.7–99.1) 0.31 96.0 (91.4–98.1)

>61

7.52 0.14 98.2 (97.0–98.9) 0.63 91.7 (87.9–94.3)

Total


5.01

0.07
98.7 (98.2–99.0)

0.37
92.5 (90.3–94.3)
Worst-case§

0–14

1.62 0.13 92.2 (87.4–97.0) 0.19 88.0 (62.3–96.2)

15–50

5.41 0.11 98.1 (97.4–98.8) 0.30 94.5 (91.9–96.2)

51–60

7.60 0.25 96.8 (95.3–98.4) 0.39 94.9 (89.9–97.4)

>61

7.52 0.44 94.4 (92.8–96.1) 0.71 90.5 (86.4–93.3)

Total

5.01 0.20 96.3 (95.5–97.0) 0.44 91.3 (88.9–93.2)

*TBE, tick-borne encephalitis; FE, field effectiveness.
†Cases/100,000 population.
‡Persons with TBE but unknown vaccination status were excluded.
§Persons with TBE but unknown vaccination status were considered regularly vaccinated.

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